Dispenser with doses counter
Abstract
There is provided a dispenser suitable for dispensing medicament, particularly medicament for use in the treatment of respiratory disorders. The dispenser comprises a housing having a support; a container, locatable within said housing, having an outlet member, wherein said container is movable relative to the housing to enable dispensing therefrom and said outlet member is connectable with said support to prevent relative movement therebetween; and a dose indicator, locatable within said housing. The container and dose indicator are reversably removable from the housing as a single unit. <IMAGE>

Term
Term ended
Expired 30 November 2019, 6.8 years ago.
- Priority
- Filed
- Granted
- Expired
- Today
23 claims: 14 independent, 9 dependent
- 1Demands Kröfur 1. Skammtari til þess að skammta laeknislyf sem samanstendur af ytra hylki (1) með burfiarstofi (5);A dispenser for dispensing a drug comprising an outer capsule (1) with a cavity (5);The above-mentioned outer capsule (1) having an outlet unit (4), a pair of said container (2), is a movable housing for the outer sleeve (1) to make it enabling the dose of said unit and said output unit (4) to be associated with said cavity unit (5) to inhibit the relative movement of pairs;and the motion limb (13), characterized by the movement of the motor member (13), has a large number of characters (the outer capsule (1) and the container (2), and the motion member (13) is removed from the outer capsule (1) as a single unit and come back and the motion sensor (13) is connected to the container (2) near the aforementioned output unit (4). iláti (2) sem er að minnsta kosti að hluta til haegt afi stafisetja inni Í fyrmefndu ytra hylki (1) sem hefur úttakseiningu (4), par sem fyrmefnt ílát (2) er hreyfanlegt mifiafi vifi ytra hylkifi (1) til pess afi gera kleift afi skammta úr pvi og fyrmefnd úttakseining (4) tengist vifi fyrmefnda burfiarstofi (5) til pess afi hindra afstæða hreyfingu pará milli;og hreyfinema(13), sem einkennist af pvi afi hreyfinemann (13) er haegt afi stafisetja inni (ytra hylkinu (1) og flátið (2) og hreyfinemann (13) eru haegt afi fjariaegja úr ytra hylkinu (1) sem eina einingu og koma fyrir aftur og hreyfineminn (13) er tengdur vifi ílátiö (2) nálægt fyrmefndri úttakseiningu (4).
- 3Skammtari I samrsemi vifi hvora sem er af krofum 1 og 2, par sem hreyfineminn 20 er útbúinn mefi gripi (10) sem er tengt vifi hálshluta ílátsins (2). A dispensing device according to any of claims 1 and 2, wherein the movable member 20 is provided with a grip (10) attached to the neck of the container (2).
- 4Dispenser 3, a pair of which the neck part is positioned on the outlet unit (4). 4. Skammtari I samrsemi vifi krofu 3, par sem hálshlutinn liggur afi efia er á úttakseiningunni (4).
- 5A sampler dispenser for each of the compartments 1 to 4, the pair of which the container (2) is a spray container. 5. Skammtari i samraemi vifi sérhverja af krofum 1 til 4, par sem ílátið (2) er úðaílát.
- 7Dispenser In accordance with Figure 6, which consists of gates (7) receiving a dose of gala, pass from the height (2) to said outlet (4). 7. Skammtari Í samrsemi vifi krfifu 6 sem samanstendur af göngum (7) sem gefnir skammtar gala farið um frá Hátinu (2) til fyrmefnds úttaks (4).
- 9Dosage In combination, any of the fractions 1 to 8, pairs as mentioned 9. Skammtari Í samraemi vifi sérhverja af krofum 1 til 8, par sem fyrmefndur 2'77 hreyfinemi (13) gefur til kynna fjölda skammta sem gefnir eru eda eftir eru Í ildtinu (2). 2'77 motion sensor (13) indicates the number of doses left in the fire (2).
- 10A dispenser according to claims 1 to 9, wherein the motion sensor (13) consists of a scanning device consisting of a pre-existing motion of the fire (2) midad at the outer sleeve (1). 10. Skammtari i samrsmi vid sdrhveija af krdfum 1 til 9, far sem hreyfineminn (13) samanstendur af vísivélbúnadi sem er komid af stad med fyrirfram dkvedinni hreyfingu á ildtinu (2) midad vid ytra hylkid (1).
- 12A dispenser according to any of claims 11, wherein the shifting device adjusts the motion sensor (13) by using a predetermined rotational movement of the first unit (14;16) driven by the movement of the center of the unit (17) d while the dose is effective. 12. Skammtari i samrsmi vid hvora sem er af krdfum 10 eda 11, far sem vfsivélbúnaðurinn stillir hreyfinemann (13) med fvf ad nota fyrirfram dkvedna snúningshreyfingu fyrstu einingarinnar (14;16) sem knúin er af hreyfingu midad vid adra einingu (17) d medan á virkni skammtarans stendur.
- 15Dispenser In accordance with claim 12 or 13, the first unit consists of a key (16) for connection to the second unit (17) through a motorized transmission time. 15. Skammtari Í samrsmi vid krdfu 12 eda 13, far sem fyrri einingin samanstendur af oki (16) til fess ad tengjast vid seinni eininguna (17) I gegnum hreyfigleypitengid.
- 20A dispenser corresponding to any one of claims 1 to 19, a pair of containers (2) containing a medicinal product that is valid from the hp consisting of albumbol, salmeterol, fluticasone prdplonate, climidated dfprdpionate, and any of the solvents of parafog and any perfume pair. 20. Skammtari ί samrsmi við sérhverja af krdfum 1 til 19, par sem ílátið (2) inniheldur lyf sem er valid úr hdpnum sem samanstendur af albúteróli, salmeteróli, flútikasón prdplonati, bekldmetasdn dfprdpionati og hvers kyns sdltum eda upplausnarefnum parafog hvers kyns bldndum paraf.
Independent claims14
84 paragraphs, as filed
Description
The invention, as a whole, relates to a dispenser having a motion element indicative of its plurality of motions. The invention relates in particular to an aerosol meter used to administer medication to medicinal products stored in a carton.
Well-known patients with medicinal products stored as an aerosol, for example, by bronchodilator medication. It is also known for use in such disease-treated drug-stored drugs that are administered to a patient by using an inhalation device consisting of a tubular outer capsule or bottle where the aerosol container is a city outlet and an outlet tube venting out of the tubular outer capsule. Aerosol dispensers used in such an inhalation device to provide predetermined doses of medication for each movement using an outlet valve assembly at one end which may open whether pressurized by the valve assembly while the container is held stationary with as the valve presses while the valve unit is stationary. When using the kit, the outer tube is provided. In a tubular outer capsule with the outlet valve of the detector connected to the load pads at the exit valve, to the dsemis nozzle of the nozzle. When the dosage is used for dosage of a drug for dermatitis in a bronchodilator disease treatment, the patient keeps the outer capsule in the top of the rupture and the mouthpiece of the nozzle in the inhalation device is in the mouth of the patient's nose. The outdoor shower is pushed towards the back of the ladder to give a dose of medicine from the container that the patient breathes. the patient keeps the outer capsule in the nest of uprooted support and the mouthpiece of the nozzle in the inhalation device is located in the mouth of the patient's nose. The outdoor shower is pushed towards the back of the ladder to give a dose of medicine from the container that the patient breathes. the patient keeps the outer capsule in the nest of uprooted support and the mouthpiece of the nozzle in the inhalation device is located in the mouth of the patient's nose. The outdoor shower is pushed towards the back of the ladder to give a dose of medicine from the container that the patient breathes.
The disadvantage of using such a known device is that the patient can not determine the amount of drug in the container as desired. If at all possible, it means that a chick who may suffer from severe bronchospasm and needs a dose of medicine will be able to dispense with the bottle permanently, because of the time when the contents are already raised.
U.S. Pat. No. 4817822 discloses a dispensers of the type described above having a dose control device, which in the first embodiment is feasible and connected at the end of the exiting portion of the aerosol dispenser. The meter for the dose selector is a catheter inside the outer capsule that stretches from the end of the outer tube to the outer surface of the tubular outer capsule. It is important for inhalation equipment containing medicinal products to be clearly labeled with the contents of the uterus so as to ensure that there is a danger of the exact incidence of the drug in question. One disadvantage in relation to the circumference of the dose reading device is that the device covers at least a portion of the outer tube and the outer capsule which creates inheritance upon labeling.
Another disadvantage of the device described is that the dispensing device is removable and connected to the aerosol dispenser, the dispensing device may be dislodged from the dispenser with the deduction that the dispenser may be used without the dispensing device or it may be fictitious at the launching device of the display device which could lead to rangs readings when the display frame is attached to the dispenser. In patients who use several different inhaler devices, even those bulbs may cause the reading device to be fixed back to the wrong dose.
In another embodiment, described in US4817822, the control device of the dose reading device is a city center inside the outer capsule and is initiated using a motion module associated with the aerosol dispenser. In the aforementioned embodiment, the outer tube can not be removed when it is inserted into the outer capsule. bath makes the cleaning of the outer capsule very inherited. Even if it is absent, the control equipment of the dose reading device would be exposed to damage by washing with water, soap, disinfectant or antiseptic solutions. This is important because the odor of many spray-free compounds separates residues that give trapped dust and impurities. Some occur with the medium for the growth of undesirable microbes.
US-A-5,622,163 discloses a motion blower for spray dispensers which is suitable for urbanization on its open-ended basic dosing cartridge.
f DE 86 02 238 You are described as a sprayer with a motion sensor assembly.
In WO96 / 16686 there is disclosed an aerosol dispenser wherein the control device of the dose analyzer is electrically and wherein the motion unit comprises a microorganism which is inserted into the wall of the outer capsule. The electronic counting device and the microphone are contained inside an airtight closed container. Such electronic components, however, are relatively expensive compared to similar mechanical equipment, typical of which is equal to five times six times more by producing it than the difference between the production volume. Such costs eventually end up on the customer and may be caused by a barrier.
US 5482030 discloses a spray dispenser having a mechanical dose analyzer, which is a city seal I and connected to an outer sheath near the outlet of the outdoor shower when connected. A robust building makes it more difficult to condense it against moisture and therefore it is difficult to wash the aforementioned dispenser without damaging the control device on the dose reading device.
Many different pharmaceutical products are sold in the form of aerosol dispensers, as described above, and peirs require missing containers and / or valves in accordance with the specified specifications. From this point of view it is plausible that there are variations in sizes between different outfits. Even the same products can cause variability due to production distortions. One problem that is common to all types of dose analyzer devices, as stated above, is that the reading device that is triggered by using switches representing the relative movement between the fleece and outer capsule lacks any behavior in order to a guide to the differences between different outbreaks. Therefore, as described above, the moles are described as being consistent with the products to be used for and can not be exchanged for other products.
Markmedidide is indicated by a doser that has motion motifs that lead at least to some of the above mentioned factors. Furthermore, the goal is to provide a patient-controlled dose-finder. Exercise high levels of vigilance in the field of fitness and activity.
According to one aspect of the invention, as discussed herein, a dose dispenser is provided for a dose of an ocular drug consisting of an outer capsule having a support; container which is located in the city center of said outer capsule having an output unit, a pair of which allow the above-mentioned container to be removed by means of a dispenser and can then be connected to the said output unit at the aforementioned support rod to prevent preventing movement of peer in between; and the motility of the city within the aforementioned outer capsule, a pair of transient infections and the dose of the outer capsule as a single unit and reverberation.
It is advisable to connect the motion sensor at the time of reach of the output module. More preferably, it is possible to connect the motion sensor to the output unit.
Conveniently, the motif is equipped with tracts that can be attached to the neck portion of the container. It is easy to fit the neck section as per the output unit.
It is advisable to have a break in a container.
It is advisable to have an outer hylk in the form of a mouthpiece. There is a danger that the number of gaps in the dosage of the pits will vary from the noise to the output.
It is advisable to administer multiple doses.
It is advisable to indicate the number of doses that are given after the shower.
Conveniently, the motion sensor consists of a calculator equipped with a pre-determined motion of the outer tube midad at the outer sleeve.
Preferably, the indexing device consists of a motion detector coupler for allowing and compensating for the extra motion of the aerosol dispenser midad at the outer sleeve.
Using a motion-type connector, it's possible to create one-piece motion blades that can hold valves and gears within braid scales of precision distortion, and may even fit multiple doses that make different sizes.
Conveniently, the display device adjusts the motion sensor by using a predetermined rotational movement of the first unit driven by the movement of the midad by the unit while the dispenser is moving.
It is advisable that the second unit stays stationary at the outer shroud while the spout is moving.
Conveniently, the former unit consists of a gear that is on a shaft through a motor of 15 and the second unit is a gate. Another advantage is that the previous unit consists of the first and the second unit $ é pole connected to the okid with the motor-type time.
The ergonomically-worn engineered wrench consists of a freestanding gear.
Conveniently, the dose is an inhalation tank that is fused with breathable water and which can be activated as a swallow upon ingestion of the user.
In accordance with the particularly preferred embodiment of the present invention, it is provided with a dispenser comprising an outer capsule for dispensing dispensers, outlet exiting the outer capsule and carrier support. In the outer capsule present for use against the outlet unit of the container and having a tunnel therein, against a pair of contents of the bottle can extend to the outlet, the output unit held firmly (the outer shell of the container and the drawer of the carton that is movable at the end of the container and the outer sleeve to the dose of the contents of the bottle moderate dosage and dose-reading device containing a dose meter indicating the remaining doses remaining in the bottle,characterized by the pvf of the dose analyzer, is securely tested at the vial near the outlet unit, and the dose-reading device is readily removed from the outer capsule as a single unit.
According to yet another embodiment of the present invention, there is provided a motile assembly for use with a dispenser comprising an outer capsule and container comprising a peripheral unit within said outer capsule having a peripheral unit, the motor assembly comprising a coupling device for You may not associate him.
It is advisable that the coupling ring is provided with grips which are securely attached to the neck portion formed around the neck. Furthermore, the neck portion is urbanized at the connection between the container and the output of units.
According to a particularly preferred embodiment of the present invention, the motion sensor assembly has motion motifs to indicate the plurality of doses given to the container in which the motion sensor assembly comprises connecting means for attaching it to the container, however, close to the output unit .
By attaching the motion sensor device to the container near the exit door, it may be possible to use the pressurized support on supported support so as to form a tight connection that fits exactly between the dose guide assembly and the outer sleeve to make it still impossible to understand it. The pad ensures the motion sensor shows detailed information about the time of flight to which it is connected.
In a preferred embodiment, the dose is a dose dispenser consisting of an outer capsule in which the time spent is a township so that there may be a discharge outlet that passes from the outer capsule, the outer end of the outer capsule provided to receive at the outlet unit of the container and having a tunnel therein around which the contents of the container can flow to the outlet, the output unit held in the outer capsule support and the peripheral capillary fluid at the periphery and the outer capsule to dose its contents into multiple doses and a window that can be seen by the dose selector .
The orientation of the dose counter near the output unit of the container in the dispenser has the potential for the facility and the effect of the same effect of current current spray rates on the meter without a meter reading device, when switched to an orodispersor in accordance with the invention, patients perceive little change midad at the usual doses that have little effect on patients and their use on the kit.
A dispenser according to the invention will be further illustrated with reference to the accompanying drawings, in which:
Figure 1 is a cross-section of a continuous inhalation device comprising a dispenser;
Figure 2 is a cross-sectional view of a dose-reading device as attached to an inhaler in the inhaler;
β
In Figure 2a, a cross section of a portion of the dosage reading apparatus here is shown in Fig.
In Figure 3, the counting table used in the dose analyzer on Figure 2 is threefold;
Figure 4 shows the root of the counting device in Figure 3;
Figure 5 shows a cross-sectional view of the second and second embodiment of the dose-reading device attached to the outer capsule of the inhaler;
In FIG. 6, the dosage laser device is unmatched in accordance with the present embodiment of the invention;
In Figure 7, the dose reading device shown in Figure 6 with the outer tube and outer capsule is uncombined
Figure 8 is a longitudinal sectional view of an inhalation device comprising the dose reading device on Figure 6 at rest position; and
Figure 9 shows an axial cross-section of the inhalation device of Figure 8 in active support.
The spraying dose as shown in Figure 1 consists of a porous outer capsule 1 which incorporates the outer container 2. The outer hylkid is open at the other end (which will be called the top of the box for the purpose of auditing the description) and the end of the other. Output 3 is hinged from the end of the end of the outer capsule 1. In the display shown, the outlet 3 is in the form of a mouthpiece that is supposed to be inserted into the mouth of the patient, but it is possible to design it as a nozzle in order to insert into the patient's nasahol.
The aerosol dispenser 2 has an outlet valve 4 at the other end. The pressure is pressed through the vent valve to release the measured dose from the aerosol dispenser. Alternatively, the valve 4 is stationary, and the valve body of the carton should be moved to the valve unit until the dose is released.
As shown clearly in Figure 1, the aerosol container 2 is the city's outer capsule 1 at the other end protruding from its open top. Thickness shafts (not shown) may appear inside the outer capsule to hold the outer upper surface of the shoulder 2 from touching the inner surface of the outer capsule 1. Burder 5 is located at the lower end of the outer capsule 1 and has a tunnel 6 there It is therefore advisable to put the valve extension 4 on the spray tank 2 and support it. The second row 7 is placed in the cage 5 and is turned towards the inner side of the outlet 3. Thus, if objects in the positions shown in Figure 1 are pushed close to the part which extends,
In Figure 2, the lower part is shown similar to that of Figure 1, but incorporates the dose reading device in accordance with the invention. The dose-wise device comprises a shaft 8 which is closely connected to the earmail by the note of the shaped portion 9 forming the food handles 10. The tubular part 9 is connected, although at the periphery of the valve arm 11, while the grip in the form of warns 10 is connected to the vicinity of the neck 12 of the valve frame 11 which is formed during assembly when ventilating valve 11 is pressed over aerosol dispenser 2. Thus, the tubular portion 9 forms and the lip 10 seals a connection to the non-buoyant cupboard when it is permanently assembled by pressing the tubular portion 9 above the valve display tube 11.
Below the pivotal part 9, the shirt 8 forms a frame 22 for securing the counting device 13 and the operating bicycle 14. The drive wheel 14 is pressed onto the drive shaft 15 of the counting unit. Drive bicycle 14 is formed by a plurality of teeth, pins 21 which can handle a plurality of gauze edges formed on the post 17 in the form of a grinder that is inserted into the outer capsule 1 and as the bottom of the outer capsule 1 parallel to valve 4.
During the 17th embodiment shown in FIG. 2, a cast portion of the outer capsule is replaced by seven other occasions where the stent 17 seals forms part of the dose analyzer. For dsemis, Fig. 2a shows the simplified representation of the dispensing device, where the paddle pin 17 can be left in the groove which is present on the body 8 of the device. The teeth that are attached to the stitch 17 are connected to the corresponding teeth on the drive wheel 14. The stern 28 acts as it passes out of the groove. However, the protrusion 24 of the chair 17 still extends to the stopper 26 and thus holds at least part of the stem 17 in the groove.
As seen in Figures 3 and 4, drive shaft 15 is connected to drive housing 16 on counting device 13.
Drive shaft 16 has a pair of shackles 18a and 18b which lie on each side of a steering wheel so that the drive shaft 16 can slope about the axle d drive shaft 15d between the first position shown in Figure 4b wherein the switching valve 18a is connected to one end of the steering wheel 19 and the other direction as seen in Figure 4d, a pair of switches 18b is connected to the other side of the sliding wheel 19. Steering wheel 19 is connected with an accessory which is described in conjunction with reference numerals 2 to 8 in Figures 1 to 3 of European patent no. 0280104, at the end of the numeral 33, which hinges the printed circuit board on the outer circumference of the groove as described below. When the countdown box 13, which is in place, is nimble, it is a city gate to be hinged at and behind the burden trough 5 until it does not interfere with a stretched pair as a male comes out of Grade 7.
The dispenser can be delivered to the patient with the dose analyzer assembled at the bottle. As a consequence, it is advisable to hand over the patient's outer sleeve 1 with the dose analyzer the city seat as shown in Figure 2 and deliver the aerosol dispenser 2 separately. In a pvf case, the patient is instructed to insert the utensil 2 into the outer sleeve 1 food guard before. At first insertion, insert the outer hylkid of the plural part 9 and vdrin 10 onto the dose reading device over the jumper of the valve display tube 11 on the uterine tube 2 pairs to 10 minutes around the neck 12. After the dose the dose analyzer is connected to the aerosol shower 2.
Adversal behavior of the dose meter at any time is shown by the following link: use of soda herpihdlkum; solid formulation; crimp; ultrasonic welding; and you wore a circular rubber flask on the box that is on the street, determined with fertilizers on the connector on the dosage. From one point of view, the most common approaches to using the most common approaches.
In order to activate the device, the part which stands out on the outer sleeve is pressed as described above with reference to Figure 1. As the outer tube carrying the dose analyzer moves within the outer capsule 1, the spinning wheel 14 starts spinning due to its engagement with the needle 17 causing rotation of drive shaft 15 and drive cam 16. As drive shaft 16 is tilted with rotation of drive shaft 15, shift switch 18a moves and connects to pivot wheel 19 (Fig. 4a) causing an increasing rotational rotation of half a tooth on the steering wheel pair to shipwheel 18a can not farther farther in this direction, the wrench is a city between the two adjacent teeth on the wheelbike (Figure 4b).In this case the drive shaft 15 can not be extended and any further movement of the outer cart into the outer carton 1 leads to the drive shaft 14 continues to rotate due to its connection to the shaft 17 with a bevel cut to the friction connections between the gear 14 and the drive shaft 15.
When the valve plug 4 has reached the maximum of filling and a multiple dose of medicine has been removed from the outer tube, the outer tube is allowed to go back to the initial position. When the aerosol dispenser and the dose analyzer return to the starting position, the operating bracket 14 starts to rotate in the opposite direction together with the drive shaft and drive shaft 16. Thus, drive gear 16 rises so that the lever 18a moves out of control wheel 19 while the lever 18b moves into engagement with it (Figure 4c), which causes a further increasing counterclockwise rotation of the toothed step on the steering wheel until seam 18b can not move further in this direction (Figure 4d).
Every time the aerosol dispenser is out of town, the steering wheel is twisted twice with increasing degrees of movement, as described above. Umrsddar movements are interpreted by the vocabulary in a video-moving movement of the typhole 33, one number of each printed disc on the numerals is clearly visible. Through the window 20 on the back of the outer capsule 1 (as shown in Figure 2), to indicate more than one dose of medicine has always been allocated. By having three digits 33 is possible, use the dose range to count as many hundred doses. As a matter of fact, the dose counter may contain more than one number of digits if the dose is less than one hundred doses. However, at the same time, it is possible to increase the number of tablets as needed if you need to store a thousand more doses.
To remove the outer tube 2 from the outer capsule to clean it, pull the extractor 2 out of the outer capsule 1 in a normal manner. When the container is pulled out, make the friction link between the drive wheel 14 and the drive shaft 15 as well as the drive shaft as necessary to bring the operating wheel in relation to the seat 17 without the selected additional count on the counting device. Once the brush has been removed, it is now possible to hit the outer sleeve 1 as described without affecting the thighs, as well as damaging the needle guards that are securely connected to the outer tube 2.
When the outer sleeve 1 is clean, the aerosol container 2 is then inserted with the dispensing device again into the outer sleeve 1. Upon insertion, the operating shaft 14 will be connected to the shaft 17 and begin to rotate until the aerosol brush reaches its edible point of view with the extension 4 of the shaft 5. operating knuckle 14, the friction knob will function like a motion liner as described above and makes any movement on the outer bush, similarly between the first connection of the operating bicycle 14 and the bush 17 and the central position of the bush 14. In this case, the friction force of the bushing taken for a long time and for different lengths of valve extensions that stand out of the jumper.
Figure 5 shows another type of motion detector which can be used in an aerosol dispenser in accordance with the invention. In the city of the toothed wheel, drive housing 16 is embodied in this embodiment of food two elongated arms 30 in which the chair 17 is secured to the collar (Figure 5a). Stack 17 is a shoulder-shaped shoulder on the upper body (not shown) that provides rough surface roughness so as to form a suitable abutment between arms 30 and shank 17 so that arms 30 will catch a shoulder 17 pair for the action as a result of which the friction is overcome.
As a result of the raising of the bucket in which the bucket and the dosing device move, the friction relationship between the arms 30 and the girl 17 causes the drive cover 16 to pivot about the axle of the shaft 15 (not shown in Figure 5) that moves the shift lever 18a into the guide wheel 19 as directed in connection with the first implementation. When the wrench 18a completes its movement, the drive cover 16 can not move further and any movement of the aerosol container into the outer sleeve 1 leads to the lower end of the pillar 17 for the loading of the friction connections. When returning to the starting point, its highest drive gear 16 In the other direction of the shuttle 16b, moves into a connection with the wheelbike 19 and can not move long. Any further movement of the casing out of outer capsule 1 leads to the bottom of the crotch tube 17.
In Figures 6 to 9, inhalation devices equipped with a electrically-powered dose analyzer are suitable in accordance with the invention. Like the machine embodiment shown above, the dose dispenser assembly comprises a shaft 40 securely connected to the outer sleeve with a pivotal portion 41 formed with grips (not shown). Partial part 41 is connected to the jaws of the valve screen 11, while a grip in the form of a guard is connected to the environment of the height of the valve panel 11. In a flat manner, the pentagonal portion 41 forms and provides a tight connection to the outer tube which is difficult to disassemble after assembly with the punched part 41 above the valve display tube 11.
Below to the shaped section 41, the shaft 40 forms a punch to attach the speaker assembly 43 and delimits the door to accommodate the host switch 44. The switch 44 is a shell made of quilt rubber and has with the container and the dose analyzer device mounted within the outer capsule with a pivotal diameter providing a necessary mining of a pin 45 stuck in an outer sleeve and protruding through a hole on a shaft 40. The magnetic friction of the rotary pin 44 on pin 45 ensures that the switch will not move along the pin unless pushed. A pair of connectors 46, 47, which consist of an electrical outlet and a circuit breaker connector, and a pair of electrical circuits also includes an electrical conductor connector, which is attached to the battery and circuit board terminals, is more in contact with the previous 48-hour shot time of the battery 48 and the printed circuit board (PCB) 49 respectively. The robesengin do not touch each other but are urban ddru on each side of pin 45 and define the upper part of the movement of the radar 44 inside your own compartment. When the roving device 44 is in its upper position, as shown in Figure 9, it contacts a rocker connector which closes the circuit between the rows due to the electrical conductivity of the silicon rubber of the radar. Although the embodiment described in the embodiment is a silica gel gauge, however, it would be a good idea if it were to be isolated from an insulating rubber that had a top-notch insertion that made non-metallic metal to some of the ddrum conductive materials. When the roving device 44 is in its upper position, as shown in Figure 9, it contacts a rocker connector which closes the circuit between the rows due to the electrical conductivity of the silicon rubber of the radar. Although the embodiment described in the embodiment is a silica gel gauge, however, it would be a good idea if it were to be isolated from an insulating rubber that had a top-notch insertion that made non-metallic metal to some of the ddrum conductive materials. When the roving device 44 is in its upper position, as shown in Figure 9, it contacts a rocker connector which closes the circuit between the rows due to the electrical conductivity of the silicon rubber of the radar. Although the embodiment described in the embodiment is a silica gel gauge, however, it would be a good idea if it were to be isolated from an insulating rubber that had a top-notch insertion that made non-metallic metal to some of the ddrum conductive materials.
In addition to its own connection at 46.47, PCB 49 also has a connection to the other switch on the battery cover and the conventional LCD display 50 is used as standard. The PCB consists of the ASIC, which is provided with the RCD, which can be used to monitor the dose, program it, and enable the operating environment as discussed below in order to keep a record of the frequency of switching power of the power cord The closed and IST LCD display shows the number of remaining doses in the aerosol dispenser. ASIC is flattered and burned in an alien manner.
In the digital city display, the LCD screen can be used to display flash signals. When the outer case is attached to the outer capsule of the drive, the LCD screen 50 is visible through the window 20. In the embodiment shown in Figure 7, the LCD screen and the window are located on the back of the outer capsule, while the door is just the same as the front door on the front of the door part of the outer capsule.
The counting box 43 is sufficiently small until it is at the end of the door and at the back of the burdarstod 5, which is cast in the outer sleeve until you do not interfere with the outbreak when it comes.
For the equipment, the part that stands out of the aerosol pair is the one that it tells. In the outer sleeve, prints as described above. When the uterus carrying the dose reading device moves inside the outer capsule from its rest position (shown in Figure 8), the host housing housing switch 44 moves a pair of upper posts to the switching pin 44 attached to pin 45, touching rocker joint 46,47 and switching valves rafrdsinni. Push the ASIC to pess to count the distance shown on the LCD LCD 50 screen. As soon as the outbreak continues, an additional dose of drug is released while the valve 44 is pressed after pin 45 for the adjustment of the fibrillation abutment at the tip pair to the valve extension after the end of the valve and the aerosol can not move further (Figure 9). On the pen, it is now possible to see the friction correction of the radar 44 at pin 45, making the additional movement of the valve plug after the switching circuit has been permanently closed as a torch acts as a motor leakage connector. The outer tube is allowed to rotate back to its starting position inside the outer capsule and when the pad is turned back, the hdlid will hold the switching pad 44 which breaks the razor when touching 46, 47 to remove the fid switch 44. Wrist 40
21 // touches the bottom of the lower surface of the switching pin 44 and pulls the switching pin up after pin 45 until the valve plug returns to its horizontal position (Figure 8).
A pair of dosage measuring devices designed for this purpose are suitable for use with missed aerosol dispensers containing a variety of doses for delivery.
ASIC designed to fit the factory in a factory The sampler of the aerosol sprayer in which the dose analyzer is installed. After assembly of the dose reading device and the first connection of the vifi battery, ASIC goes into the self-test phase. A couple of times you can get to the programming phase by pressing the switch, which allows you to program it for you to count on the corresponding number of doses (eg.
200, 120, 80, 60). It is a good idea to make an impact on a roundabout. After programming goes
ASIC in a telephoto pair, which the LCD monitor considers to be sufficient when the circuit break is interrupted. When the number zero is reached, the ASIC model is used to prevent the grandfather from being counted further. In order to prevent false reading due to the impact of an electrical shock, it is important to design ASIC in order to determine the quality of the battery after the battery has been permanently shut down in a predetermined amount of time. (The case of the aerosol dispenser fits the active function after the function of the electrical circuit is interrupted due to mechanical damage caused by the design of the ASIC to fit the LCD display to this end of the user's problem.
As in other embodiments of the invention described above, the cane can be pulled out of the outer capsule in a normal manner. As soon as the container is pulled out, the shirt 40 pulls up the pinion pin after pin 45 pairs until it completely drops the pin. The remote control cable has a remote control, which is easy to use, without compromising the speed of the dose reading device that is securely connected to the aerosol dispenser.
At the end of the aerosol dispensation, the patient may feel the paws of the dose-reading device are turned correctly with respect to the outer capsule for studying the propagation of the scalp, associated with rofaienna 44, and is pushed with a pin 45 pairs to the upper leg of the rocket joint. Further insertion of the aerosol dispenser will result in the switching pin 44 pushed for pin 45 pairs until the valve plug is restored inside the cage 5.
It is important to use the ASIC programming to use only one of the dose analyzer devices, as well as many different aerosol dispensers with missed space. For the test of the switching device, it is also important to use the same design of the dose analyzer with different valves having a few valve alternatives and different low-noise specifications.
In the present invention, which has been described in detail, that there is a spray dispenser that can be triggered by a handgun by the patient, it is highly important to use other start-up procedures instead. The special use of inhalation13, controlled by respiratory tract, a pair of functionally enhanced food and a gastrointestinal infection, is initiated by patient inhalation, is also shown.
The dosage form of the invention is suitable for the dosage of a prodrug, especially in the treatment of respiratory disturbances. Video-taking drugs go well for a better choice of hdp, such as painkillers, for example. codeine, dihydromorphine, ergotamine, fentanyl eda morphine; aggressive combinations, eg diltiazem; allergic drugs, for example, chromoglycate, ketotifene and nedochromil; infectious agents such as cephalosporin, pensillin, streptomycin, sulfonamide, tetracycline and pentamidine; andhistamine, for example. methapyrilene; bdlgueydandi drug, for example. cyclosporin dipotonate, fluticasone propionate, flunisolide, budesonide, rofleponide, mometasone furoate ada triamidonone asetonide; antitussive drugs, eg noscapine; bronchodilators, eg albuterol, salmeterol, efedrin, adrenaline, phenotardl, formoterol fosophenaline, metaprostenendl, phenylenaline, phenylpropanilamine, pherbuterol, reprdterdl, rimiterdl, terbutaline,<sub>;</sub> insulin or glucagon. In the form of salts, such as alkali metal salts such as acidic acid salts (eg low alkyl esters) as solvents, the drug may be used as an adjuvant (eg hydrated) to maximize the activity and / or balance of the drug.
The main drugs are selected from albumin, salmeterdli, fluticasprdionate and clot matrix dfprdptonate, and the solvents of such solvents, for example, Salvatide sulphate and xinafdatide salmeteride.
Drugs are also handed over in combinations. Preferred formulations containing active ingredient compositions contain salbutamdl (for example, as free base or sulphate salt) or salmeterid (eg as xfnafdate salt) In combination with bdlgueydandi starches such as epithionic ester (eg diprdpionatide) or fluticasone ester (eg propionate).
This will be a bit of a long time, since the invention has already been explained, and the invention further adds to variations, distortions and rewrites.
The application, the description and the form of the form, which may be used as a basis for priority rights by pvf, includes all of the following statements. The following can be used to reverse the characteristics of such a particular combination of features described in Figure F. They can be used in the process of managing, using the requirements and the content of the data, using and without limitation, one more of the following requirements :
8 sheets
Sheet 1 Sheet 2 Sheet 3 Sheet 4 Sheet 5 Sheet 6 Sheet 7 Sheet 8
117 members in 38 offices
Priority claims11
| Document | Office | Kind | Date |
|---|---|---|---|
| 9711889 | United Kingdom | A | |
| 9711889 | United Kingdom | A | |
| 9721875 | United Kingdom | A | |
| 9721875 | United Kingdom | A | |
| 9803377 | European Patent Office (EPO) | W | |
| 9803377 | European Patent Office (EPO) | W | |
| 97218754 | – | – | – |
| GB19970011889 | – | – | – |
| GB19970021875 | – | – | – |
| PCTEP9803377 | – | – | – |
| WO1998EP03377 | – | – | – |
Members117
| Document | Office | Kind | |
|---|---|---|---|
| GB9711889D0 | United Kingdom | D0 | |
| GB9721875D0 | United Kingdom | D0 | |
| CA2293484A1 | Canada | A1 | |
| CA2293487A1 | Canada | A1 | |
| CA2293488A1 | Canada | A1 | |
| CA2486892A1 | Canada | A1 | |
| CA2486894A1 | Canada | A1 | |
| WO9856444A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO9856445A1 | World Intellectual Property Organization (WIPO) | A1 | |
| WO9856446A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU8213798A | Australia | A | |
| AU8213898A | Australia | A | |
| AU8436498A | Australia | A | |
| MA24562A1 | Morocco | A1 | |
| HRP980304A2 | Croatia | A2 | |
| CO4830464A1 | Colombia | A1 | |
| PE99099A1 | Peru | A1 | |
| IS5282A | Iceland | A | |
| ZA984944B | South Africa | B | |
| NO996085D0 | Norway | D0 | |
| AP9901705A0 | African Regional Intellectual Property Organization (ARIPO) | A0 | |
| NO996085L | Norway | L | |
| EP0986412A1 | European Patent Office (EPO) | A1 | |
| EP0988077A1 | European Patent Office (EPO) | A1 | |
| EP0988078A1 | European Patent Office (EPO) | A1 | |
| BR9809554A | Brazil | A | |
| EA199901017A1 | Eurasian Patent Organization (EAPO) | A1 | |
| ID24128A | Indonesia | A | |
| TR1999003066T2 | Türkiye | T2 | |
| TR199903066T2 | Türkiye | T2 | |
| BR9809980A | Brazil | A | |
| BR9809983A | Brazil | A | |
| PL337316A1 | Poland | A1 | |
| CN1265601A | China | A | |
| HK1023956A | Hong Kong, China | A | |
| HK1023956A1 | Hong Kong, China | A1 | |
| JP2000513632A | Japan | A | |
| JP2000513633A | Japan | A | |
| JP2000513634A | Japan | A | |
| AR012939A1 | Argentina | A1 | |
| EA001396B1 | Eurasian Patent Organization (EAPO) | B1 | |
| KR20010013630A | Republic of Korea | A | |
| HU0003328A2 | Hungary | A2 | |
| HUP0003328A2 | Hungary | A2 | |
| IL133219A0 | Israel | A0 | |
| IL133219D0 | Israel | D0 | |
| HU0003328A3 | Hungary | A3 | |
| HUP0003328A3 | Hungary | A3 | |
| YU65799A | Yugoslavia, later Serbia and Montenegro (until 2006) | A | |
| EG21520A | Egypt | A | |
| AU741218B2 | Australia | B2 | |
| AU741693B2 | Australia | B2 | |
| EP1163922A2 | European Patent Office (EPO) | A2 | |
| AU742913B2 | Australia | B2 | |
| US6360739B1 | United States of America | B1 | |
| EP0986412B1 | European Patent Office (EPO) | B1 | |
| AT215389T | Austria | T | |
| ATE215389T1 | Austria | T1 | |
| NZ501379A | New Zealand | A | |
| DE69804609D1 | Germany | D1 | |
| DK0986412T3 | Denmark | T3 | |
| US6431168B1 | United States of America | B1 | |
| DE69804609T2 | Germany | T2 | |
| PT986412E | Portugal | E | |
| EP1163922A3 | European Patent Office (EPO) | A3 | |
| US6474331B1 | United States of America | B1 | |
| ES2175737T3 | Spain | T3 | |
| AP1126A | African Regional Intellectual Property Organization (ARIPO) | A | |
| US2002195102A1 | United States of America | A1 | |
| TW533865U | Taiwan Province of China | U | |
| HRP980304B1 | Croatia | B1 | |
| US6601582B2 | United States of America | B2 | |
| EP0988077B1 | European Patent Office (EPO) | B1 | |
| AT251481T | Austria | T | |
| ATE251481T1 | Austria | T1 | |
| DE69818819D1 | Germany | D1 | |
| US2003209239A1 | United States of America | A1 | |
| DK0988077T3 | Denmark | T3 | |
| JP3487865B2 | Japan | B2 | |
| JP3487866B2 | Japan | B2 | |
| JP3487867B2 | Japan | B2 | |
| PT988077E | Portugal | E | |
| IN192609B | India | B | |
| CN1150038C | China | C | |
| ES2207841T3 | Spain | T3 | |
| DE69818819T2 | Germany | T2 | |
| EP1163922B1 | European Patent Office (EPO) | B1 | |
| AT274952T | Austria | T | |
| ATE274952T1 | Austria | T1 | |
| DE69826039D1 | Germany | D1 | |
| EP1475116A2 | European Patent Office (EPO) | A2 | |
| DK1163922T3 | Denmark | T3 | |
| IL133219A | Israel | A | |
| PT1163922E | Portugal | E | |
| ES2227031T3 | Spain | T3 | |
| PL188988B1 | Poland | B1 | |
| KR100493837B1 | Republic of Korea | B1 | |
| DE69826039T2 | Germany | T2 | |
| EP0988078B1 | European Patent Office (EPO) | B1 | |
| AT305320T | Austria | T |
Numbers
- Publication, DOCDB
- 2177
- Publication, EPODOC
- IS2177B
- Application
- 5282
- Application, DOCDB
- 5282
- Application, EPODOC
- IS19990005282
Titles2
- Icelandic
- Skammtari með lyfjaskammtateljara
- English
- Dosage with dose meter
Classification
- CPC, 9
- A61M15/009
- A61M15/00
- A61M15/0091
- A61M15/0068
- A61M15/0076
- A61M15/008
- A61M15/0081
- A61P11/06
- A61P11/08
- IPC, 5
- A61J
- A61M11 00
- A61M15 00
- B65D
- G01F