Surfactant-free, water-free, foamable compositions and breakable foams and their uses
Abstract
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Term
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32 claims: 2 independent, 30 dependent
- 1218866/3 Claims 1. A surfactant free and substantially foam adjuvant free foamable composition comprising:a carrier comprising: a) about 40% to about 92% by weight of the carrier of a hydrophobic solvent;b) about 8% to about 50% by weight of the carrier of a wax comprising a paraffin wax ;and a liquefied or compressed gas propellant;and a tetracycline antibiotic;wherein the ratio of the carrier to propellant is from about 100:1 to about 100:30;and wherein the total weight of the hydrophobic solvent and wax together is between about 85% and about 100% by weight of the carrier;and wherein upon dispensing, the foamable carrier composition from a container, the composition forms a breakable foam that is stable, yet breaks easily upon application of shear force.
- 19A surfactant free and substantially foam adjuvant free foamable composition comprising:a carrier comprising: a) about 40% to about 92% by weight of the carrier of a hydrophobic solvent;b) about 8% to about 50% by weight of the carrier of a wax comprising a paraffin wax selected from the group consisting of a paraffin wax 58-62 °C, a paraffin wax 5153 °C, and a paraffin wax 42-44 °C, or mixtures thereof;and a liquefied or compressed gas propellant, wherein the gas propellant has a vapor pressure of about 40 to about 90 psi;the carrier to propellant is from about 100:1 to about 100:30;wherein the total weight of the hydrophobic solvent and wax together is between about 85% and about 100% by weight of the carrier;wherein the foamable composition is flowable;and 84 218866/3 wherein upon dispensing, the foamable composition from a container, the composition forms a breakable foam that is stable, yet breaks easily upon application of shear force.
Independent claims2
7 paragraphs in 1 section, as filed
218866/2
SURFACTANT-FREE, WATER-FREE, FOAMABLE COMPOSITIONS AND BREAKABLE FOAMS AND THEIR USES
[0001] [Canceled]
BACKGROUND
[0002] Foam compositions with high amounts of hydrophobic solvents are little known in the art. US Patent Application, Publication No. 2008/0206159 relates to a waterless composition and foam as a vehicle in which an active pharmaceutical or cosmetic agent, when added is stable or stabilized by or its destabilization is impeded by the presence of a modulating agent. US Patent Application, Publication No. 2009/0041680 relates to foamable vehicles or carriers comprising at least one wax, waxy substance, counterpart or derivative, a stabilizer, water, and a propellant.
[0003] Foams and, in particular, oleaginous single-phase foams are complicated systems which do not form under all circumstances. Slight shifts in foam composition, such as by the addition of active ingredients or the removal of any of the essential ingredients, may destabilize the foam.
[0004] The prior art teaches oleaginous foam compositions require significant amounts of surface active agents to form and stabilize a foam. These compositions require various standard surfactants, as essential components.
[0005] Surfactants are known as essential ingredients in foam compositions because of their amphiphilic properties and because they are considered essential in forming a foam. However, many surfactants are known to be irritating when left on the skin, as they can extract lipids from - 1 -
110 members in 11 offices
Priority claims24
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Numbers
- Publication
- 218866
- Publication, DOCDB
- 218866
- Publication, EPODOC
- IL218866
- Application
- 218866
- Application, DOCDB
- 21886612
- Application, EPODOC
- IL20120218866
Titles2
- English
- Surfactant-free, water-free, foamable compositions and breakable foams and their uses
- Hebrew
- ???????, ?????? ???? ???? ??? ??????? ???, ??????? ??????, ????? ?????? ?????????
Classification
- CPC, 70
- A61K47/44
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