Medicament cartridge having identification means

The present invention relates to a medicament cartridge, having particular, but not exclusive application for use with a medication delivery apparatus. The invention provides a medication cartridge that maybe dedicated to a particular medication delivery apparatus. A medication delivery apparatus may take the form of, for example, an injector pen or an infuser apparatus.

It is known׳that a person providing themselves, or others, with a medicament regimen may require more than one medicament as part of that regimen. For example many of those having diabetes take a combination of slow and fast acting types of insulin. It is important that the different forms of medicament do not become confused and that the patient does not receive the incorrect medicament.

By providing a cartridge that can be dfedicated to a particular form of medicament, this problem may be eliminated or at least substantially reduced. For example, such a cartridge may only be accepted by a certain medication delivery apparatus or might not permit the proper functioning of certain medication delivery apparatus.

WO 01/56635 for example, describes a container for a substance, which container comprises a coupling element for coupling the container with an administration unit for the substance, and a recognition element associated with the container. WO/0156635 further describes a device for administering a substance, which device comprises a coupling device for receiving a coupling element of a container containing the substance, and a sensor element that reads information out of or inscribes information into the recognition element and/or that detects the state of the container.

WO 95/13841 describes a hand-held power injector for injecting liquid, such as contrast media, into the vascular system of a mammal. The device comprises a pistol-shaped housing, which encloses a battery-powered D.C. motor for constant-rate delivery of liquid from a syringe. The hand-held power injector includes an engagement feature connecting the syringe la and the power injector, which prevents inadvertent activation of the power injector. The engagement feature comprises a flange on the syringe arranged to engage in a slot of the casing and to operate a syringe sensing switch, thereby permitting power assisted injection to be commenced by a user.

US 6,110,152 describes a cartridge for containing a fluid and for use with an electronic delivery device, includes a cartridge housing for holding the fluid, and information providing source. The information providing source is coupled to the cartridge housing to operatively couple with the electronic delivery device to provide predetermined information regarding the cartridge to the electronic delivery device. Alternatively, the information providing source is a bar code that provides the predetermined information to electronic delivery device by reading of the bar code. The cartridge may be used in a system that includes an electronic delivery device, such as an electronic pen-type injector and/or infusion pump.

However, none of the these publications discloses the medicament delivery apparatus comprising a processor and a plurality of switches, with tripping of a particular switch indicating the presence of a medicament cartridge containing a particular medicament. This has the advantage that the type of medicament in the cartridge can be automatically detected by means of the particular switch, which is tripped.

According to the present invention, in combination a medicament delivery apparatus and a medicament cartridge are provided, the medicament delivery apparatus including at least one switch and the medicament cartridge comprising a cartridge housing within which a medicament is provided, a displaceable piston located internally at one end of the housing and araised ring of material about an external periphery of the medicament cartridge, the ring of material being of sufficient dimensions, in use, to trip the at least one switch of the medicament delivery apparatus.

Preferably a location of the raised ring of material along a longitudinal axis of the cartridge housing provides an indication of the medicament contained within the medicament cartridge.

WO 03/047665

Preferably the raised ring of material may be colour coded to provide an indication of the medicament contained within the medicament cartridge.

Preferably the raised ring of material is defined by a first inner surface that conforms to a peripheral surface of the cartridge and a second outer surface. More preferably, the second outer surface provides a smooth rounded surface. Advantageously, a shape of the outer surface of the raised ring of material provides an indication of the medicament contained within the medicament cartridge.

Preferably the medication delivery apparatus further comprises a display, the processor casing the display to show information relating to the medicament cartridge within the medication delivery apparatus.

Preferably unless the at least one switch is tripped the medication delivery apparatus will not function.

The invention will now be described, by way of example only, with reference to the accompanying drawings in which:

Figure 1 shows a medicament cartridge in accordance with the first aspect of the invention; Figure 2 shows schematically a part of a first medication delivery apparatus for use with a medicament cartridge in accordance with the first aspect of the invention; and

Figure 3 shows schematically apart of a second medication delivery apparatus for use with a medicament cartridge in accordance with the first aspect of the invention

Referring to Figure 1, there may be seen a medicament cartridge 2 in accordance with the present invention.

The medicament cartridge comprises a cartridge housing 4 having an openneck at a first end. The open neck is provided with an external flange. A flexible fluid impermeable membrane 6 is sealingly secured across the neck by a cap 8 secured against the flange. The metal cap 8 has a central opening through which the membrane 6 is exposed. In use, a needle of a needle unit penetrates the membrane 6.

WO 03/047665

The medicament is contained within a chamber defined by the cartridge housing 4, the flexible membrane 6 at the first end of the cartridge housing and a displaceable piston 14 (shown in ghost) located at a second end of the cartridge housing 4. Movement of the piston 14 towards the first end of the cartridge housing 4 causes the medicament to be dispensed through the needle unit.

The medicament cartridge of the present invention is additionally provided with a raised ring 10 of material about an external periphery of the cartridge housing 4. The raised ring 10 of material may be formed of any suitable material by any suitable method.

In the illustrated embodiment, the raised ring '10 of material is defined by a first inner surface that conforms to a peripheral surface of the cartridge housing 4 and a second outer surface 12. In the illustrated embodiment, the raised ring 10 is of generally rectangular section. The second outer surface 12 is shown as a smooth rounded surface. The raised ring 10 maybe formed as a moulding of a plastics material about the cartridge housing 4. This may occur prior to filling or loading of the medicament cartridge with medicament. In such a case the location of the raised ring 10 may be used during the filling or loading operation to ensure that the medicament cartridge receives the correct medicament.

Since location of the raised ring 10 is determined during manufacture, and as such is a highly repeatable operation, the location of the raised ring 10 may be used as an indication of the medicament contained within the medicament cartridge.

Thus, a medicament delivery apparatus (Figure 2) maybe provided with aprocessor 22 and a switch 20. When the switch 20 is tripped this allows the .medicament delivery apparatus to function. If the switch 20 is not tripped, either because there is no raised ring 10 present, or is present at an incorrect location along a longitudinal axis of the medicament cartridge inserted, such a medicament delivery apparatus will not operate.

Alternatively, a medication delivery apparatus may comprise aprocessor 34 and aplurality of switches 30,32, tripping of a particular switch indicating the presence of a medicament

WO 03/047665 cartridge containing a particular medicament within the medication delivery apparatus. The medication delivery apparatus may further comprise a display 36, the processor 34 causing the display to show information relating to the medicament cartridge within the medication delivery apparatus, for example whether the medicament is a fast acting or slow acting form 5 of medicament. This has the advantage that it provides a user with an additional opportunity to check that the correct medicament is to be dispensed. Optionally, the processor 34 may actuate a drive mechanism 38 to express medicament from the cartridge 2.

It will be understood that quite small differences in location may be enough to enable a » medication delivery apparatus to distinguish between medicament cartridges having differing contents. However, such differences may not be readily apparent to all users of the cartridges, for example those with impaired vision. For this reason, the raised ring 10 may also be formed of a material of a particular colour to indicate a particular medicament within a medicament cartridge. Alternatively, or additionally, the raised ring 10 may also be formed 15 in a particular shape to indicate a particular medicament within a medicament cartridge. This may be of particular advantage to those having more seriously impaired vision.