ES3013301T3
Methods for determining drug efficacy using ikzf3 (aiolos)
Abstract
The invention relates to the use of the cereblon-associated proteins IKZF1 (Ikaros) and IKZF3 (Aiolos) as biomarkers for indicating the efficacy of a compound in altering the immune response in a subject and for evaluating the efficacy of a compound in treating cancer or an inflammatory disease, as well as a kit comprising the compound and a means for identifying the biomarkers. (Automatic translation with Google Translate, no legal value)

Term
6.8 yearsto projected expiry
Projected expiry 28 June 2033, counted from filing; an application has no term until it is granted.
- Priority
- Filed
- Published
- Today
- Projected expiry
72 sheets
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22 members in 7 offices
Priority claims4
| Document | Office | Kind | Date |
|---|---|---|---|
| 201261666703P | United States of America | – | |
| 201261666703 | United States of America | P | |
| 201261696752P | United States of America | – | |
| 201261696752 | United States of America | P |
Members22
| Document | Office | Kind | |
|---|---|---|---|
| CA2877736A1 | Canada | A1 | |
| CA3136093A1 | Canada | A1 | |
| WO2014004990A2 | World Intellectual Property Organization (WIPO) | A2 | |
| US2014162282A1 | United States of America | A1 | |
| WO2014004990A3 | World Intellectual Property Organization (WIPO) | A3 | |
| EP2867671A2 | European Patent Office (EPO) | A2 | |
| MX2014016014A | Mexico | A | |
| JP2015528112A | Japan | A | |
| US9857359B2 | United States of America | B2 | |
| JP6318152B2 | Japan | B2 | |
| US2018209961A1 | United States of America | A1 | |
| MX358517B | Mexico | B | |
| EP2867671B1 | European Patent Office (EPO) | B1 | |
| ES2699810T3 | Spain | T3 | |
| EP3489682A1 | European Patent Office (EPO) | A1 | |
| EP3489682B1 | European Patent Office (EPO) | B1 | |
| EP3904875A1 | European Patent Office (EPO) | A1 | |
| EP3904875A4 | European Patent Office (EPO) | A4 | |
| ES2872967T3 | Spain | T3 | |
| CA2877736C | Canada | C | |
| EP3904875B1 | European Patent Office (EPO) | B1 | |
| ES3013301T3This record | Spain | T3 |
Numbers
- Publication
- 3013301
- Application
- 21164678
Titles
- English
- METHODS FOR DETERMINING DRUG EFFICACY USING IKZF3 (AIOLOS)
Classification
- CPC, 7
- G01N33/5047
- G01N33/5052
- G01N33/5023
- G01N2800/101
- G01N2800/104
- G01N2800/52
- G01N33/57505
- IPC, 1
- G01N33 50