Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors

Provided herein are compounds of Formula I: (I) or a pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have meanings given in the specification, which are RET kinase inhibitors and are useful in the treatment and prevention of diseases that can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders. </p> <p>(Automatic translation with Google Translate, without legal value)