EP4491184A3
Channel modulators
Abstract
The inventions relate to compositions and articles of manufacture comprising connexin modulators, pannexin modulators, gap junction modulators, hemichannel modulators, and pannexin channel modulators and their use, alone or in combination, in treating ocular and other disorders.

Term
8.9 yearsto projected expiry
Projected expiry 21 August 2035, counted from filing; an application has no term until it is granted.
- Priority and filed
- Published
- Today
- Projected expiry
1 sheet
Sheet 1
Every citation, both ways
| Document | Relation | Office | Cited during |
|---|---|---|---|
| WO2009147442A1 | Cites | World Intellectual Property Organization (WIPO) | Search report |
| WO2011067608A1 | Cites | World Intellectual Property Organization (WIPO) | Search report |
| US2013281524A1 | Cites | United States of America | Search report |
| US2014011773A1 | Cites | United States of America | Search report |
| EP2586436A1 | Cites | European Patent Office (EPO) | Search report |
| A. AKOPIAN ET AL: "Gap Junction-Mediated Death of Retinal Neurons Is Connexin and Insult Specific: A Potential Target for Neuroprotection", THE JOURNAL OF NEUROSCIENCE : THE OFFICIAL JOURNAL OF THE SOCIETY FOR NEUROSCIENCE, vol. 34, no. 32, 6 August 2014 (2014-08-06), pages 10582 - 10591, XP055243551, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.1912-14.2014 | Non-patent | – | Search report |
| KIM YERI ET AL: "Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels", NEUROTHERAPEUTICS, ELSEVIER INC, US, vol. 14, no. 4, 30 May 2017 (2017-05-30), pages 1148 - 1165, XP036379953, ISSN: 1933-7213, [retrieved on 20170530], DOI: 10.1007/S13311-017-0536-9 | Non-patent | – | Search report |
35 members in 9 offices
Members35
| Document | Office | Kind | |
|---|---|---|---|
| CA2958879A1 | Canada | A1 | |
| WO2016029191A2 | World Intellectual Property Organization (WIPO) | A2 | |
| US2016177298A1 | United States of America | A1 | |
| WO2016029191A3 | World Intellectual Property Organization (WIPO) | A3 | |
| AU2015305269A1 | Australia | A1 | |
| EP3183346A2 | European Patent Office (EPO) | A2 | |
| EA201790434A1 | Eurasian Patent Organization (EAPO) | A1 | |
| CN107109410A | China | A | |
| JP2017526687A | Japan | A | |
| HK1243457A | Hong Kong, China | A | |
| HK1243457A1 | Hong Kong, China | A1 | |
| EP3183346A4 | European Patent Office (EPO) | A4 | |
| US10465188B2 | United States of America | B2 | |
| JP6683686B2 | Japan | B2 | |
| JP2020114847A | Japan | A | |
| US2020239889A1 | United States of America | A1 | |
| US2020263175A1 | United States of America | A1 | |
| US2021115445A1 | United States of America | A1 | |
| CN107109410B | China | B | |
| AU2015305269B2 | Australia | B2 | |
| AU2021282410A1 | Australia | A1 | |
| CN114010788A | China | A | |
| US11401516B2 | United States of America | B2 | |
| JP7185655B2 | Japan | B2 | |
| JP2023022154A | Japan | A | |
| US2023174980A1 | United States of America | A1 | |
| AU2024201060A1 | Australia | A1 | |
| EP3183346B1 | European Patent Office (EPO) | B1 | |
| EP3183346C0 | European Patent Office (EPO) | C0 | |
| EP4491184A2 | European Patent Office (EPO) | A2 | |
| JP2025038085A | Japan | A | |
| EP4491184A3This record | European Patent Office (EPO) | A3 | |
| US2025136987A1 | United States of America | A1 | |
| JP7781731B2 | Japan | B2 | |
| AU2026200926A1 | Australia | A1 |
28 legal events, as 2 offices reported them to INPADOC
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| First examination report despatched17Q | 17Q | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: EXAMINATION IS IN PROGRESSSTAA | STAA | EP | |
| Request for examination filed17P | 17P | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: REQUEST FOR EXAMINATION WAS MADESTAA | STAA | EP | |
| Designated contracting statesAK | AK | EP | |
| Information provided on ipc code assigned before grantRIC1 | RIC1 | EP | |
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| Information provided on ipc code assigned before grantRIC1 | RIC1 | EP | |
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| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Amendment of ipc main classPREVIOUS MAIN CLASS: A61K0031570000R079 | R079 | DE | |
| Divisional application: reference to earlier applicationAC | AC | EP | |
| Designated contracting statesAK | AK | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: THE APPLICATION HAS BEEN PUBLISHEDSTAA | STAA | EP |
Numbers
- Publication
- 4491184
- Application
- 242022192
Titles3
- German
- KANALMODULATOREN
- English
- CHANNEL MODULATORS
- French
- MODULATEURS DE CANAUX
Classification
- CPC, 19
- A61K38/08
- C12N15/113
- A61K38/39
- A61K9/0048
- A61K31/167
- A61K31/195
- A61K31/382
- A61K31/498
- A61K31/5377
- A61K31/557
- A61K31/5575
- A61K31/575
- C12N15/1138
- C12N2310/11
- C12N2310/3231
- A61P27/02
- A61K38/10
- A61K45/06
- A61K31/713
- IPC, 17
- A61K31 167
- C12N15 113
- C07H21 02
- A61K31 7125
- A61P27 02
- A61K31 352
- A61K38 08
- A61K38 10
- A61K38 39
- A61K45 06
- A61K9 00
- A61K31 195
- A61K31 382
- A61K31 498
- A61K31 53
- A61K31 55
- A61K31 57
Designated states38
- Contracting states, 38
- Albania
- Austria
- Belgium
- Bulgaria
- Switzerland
- Cyprus
- Czechia
- Germany
- Denmark
- Estonia
- Spain
- Finland
- France
- United Kingdom
- Greece
- Croatia
- Hungary
- Ireland
- Iceland
- Italy
- Liechtenstein
- Lithuania
- Luxembourg
- Latvia
and 14 moreShow fewer
- Monaco
- North Macedonia
- Malta
- Netherlands (Kingdom of the)
- Norway
- Poland
- Portugal
- Romania
- Serbia
- Sweden
- Slovenia
- Slovakia
- San Marino
- Türkiye