Nova Patents
EP4282467A2

Spinal cord stimulation system determining optimal sub-perception therapy by using neural dose

Abstract

The present invention relates to a spinal cord stimulator device, comprising a plurality of electrodes insertable within a patient's spinal column, and control circuitry programmed to provide sub-perception stimulation pulses to a patient's tissue at at least one of the plurality of electrodes in accordance with a stimulation program defined by a plurality of stimulation parameters including pulse frequency, wherein the stimulation parameters comprise an energy and a frequency that is on or within one or more linearly-bounded regions defined by points (i) (10 Hz, 6 µC/s), (10 Hz, 12 µC/s), (50 Hz, 55 µC/s), and (50 Hz, 27 µC/s); or (ii) (50 Hz, 27 µC/s), (50 Hz, 55 µC/s), (100 Hz, 88 µC/s), and (100 Hz, 40 µC/s); or (iii) (100 Hz, 40 µC/s), (100 Hz, 88 µC/s), (200 Hz, 151 µC/s), and (200 Hz, 67 µC/s); or (iv) (200 Hz, 67 µC/s), (200 Hz, 151 µC/s), (400 Hz, 274 µC/s), and (400 Hz, 118 µC/s).

EP4282467A2, drawing sheet 1
Sheet 1 of 74

Term

13.8 yearsto projected expiry

Projected expiry 1 July 2040, counted from filing; an application has no term until it is granted.

  1. Priority
  2. Filed
  3. Published
  4. Today
  5. Projected expiry

14 claims: 2 independent, 12 dependent

  1. 1
    A spinal cord stimulator device, comprising:a plurality of electrodes insertable within a patient's spinal column;and control circuitry programmed to provide sub-perception stimulation pulses to a patient's tissue at at least one of the plurality of electrodes in accordance with a stimulation program defined by a plurality of stimulation parameters including pulse frequency, wherein the stimulation parameters comprise an energy and a frequency that is on or within one or more linearly-bounded regions defined by points: (i) (10 Hz, 6 µC/s), (10 Hz, 12 µC/s), (50 Hz, 55 µC/s), and (50 Hz, 27 µC/s);or (ii) (50 Hz, 27 µC/s), (50 Hz, 55 µC/s), (100 Hz, 88 µC/s), and (100 Hz, 40 µC/s);or (iii) (100 Hz, 40 µC/s), (100 Hz, 88 µC/s), (200 Hz, 151 µC/s), and (200 Hz, 67 µC/s);or (iv) (200 Hz, 67 µC/s), (200 Hz, 151 µC/s), (400 Hz, 274 µC/s), and (400 Hz, 118 µC/s).
  2. 8
    A spinal cord stimulator device, comprising:a plurality of electrodes insertable within a patient's spinal column;and control circuitry programmed to provide sub-perception stimulation pulses to a patient's tissue at at least one of the plurality of electrodes in accordance with a stimulation program defined by a plurality of stimulation parameters including a frequency, a current amplitude, and a pulse width that is on or within one or more linearly-bounded volumes defined by points (in Hz, mA, µs): (i) (10, 1.73, 326), (10, 1.73, 374), (10, 3.39, 326), (10, 3.39, 374), (50, 1.65, 283), (50, 1.65, 333), (50, 3.43, 283), (50, 3.43, 333);or (ii) (50, 1.65, 283), (50, 1.65, 333), (50, 3.43, 283), (50, 3.43, 333), (100, 1.82, 233), (100, 1.82, 271), (100, 3.42, 233), (100, 3.42, 271);or (iii) (100, 1.82, 233), (100, 1.82, 271), (100, 3.42, 233), (100, 3.42, 271), (200, 1.66, 181), (200, 1.66, 237), (200, 3.52, 181), (200, 3.52, 237);or (iv) (200, 1.66, 181), (200, 1.66, 237), (200, 3.52, 181), (200, 3.52, 237), (400, 1.76, 162), (400, 1.76, 204), (400, 3.48, 162), (400, 3.48, 204).
Independent claims2