EP2604110A3

Animal models and therapeutic molecules

Abstract

The invention discloses methods for the generation of chimaeric human - non human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.

Term

Projected expiry 7 July 2030.

Every citation, both ways

Citations
Document	Relation	Office	Cited during
WO02066630A1	Cites	World Intellectual Property Organization (WIPO)	Search report
US2006015957A1	Cites	United States of America	Search report
WO2007117410A2	Cites	World Intellectual Property Organization (WIPO)	Search report
WO2008094178A2	Cites	World Intellectual Property Organization (WIPO)	Search report
WO2009080254A1	Cites	World Intellectual Property Organization (WIPO)	Search report
SHULTZ L D ET AL: "Humanized mice in translational biomedical research", THE JOURNAL OF IMMUNOLOGY, NATURE PUB. GROUP, vol. 7, no. 2, February 2007 (2007-02-01), pages 118 - 130, XP002493022, ISSN: 1474-1733, DOI: 10.1038/NRI2017	Non-patent	–	Search report
LONBERG NILS: "Human antibodies from transgenic animals", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 23, no. 9, September 2005 (2005-09-01), pages 1117 - 1125, XP002442149, ISSN: 1087-0156, DOI: 10.1038/NBT1135	Non-patent	–	Search report

432 members in 26 offices

This recordMember, by publication date16 more offices are in the list below

Members432

Family members, oldest first
Document	Office	Kind
GB609904A	United Kingdom	A	1948-10-08
GB0911846D0	United Kingdom	D0	2009-08-19
GB0913102D0	United Kingdom	D0	2009-09-02
CA2767436A1	Canada	A1	2011-01-13
WO2011004192A1	World Intellectual Property Organization (WIPO)	A1	2011-01-13
GB201116120D0	United Kingdom	D0	2011-11-02
GB201116122D0	United Kingdom	D0	2011-11-02
CA2802591A1	Canada	A1	2011-12-22
WO2011158009A1	World Intellectual Property Organization (WIPO)	A1	2011-12-22
GB201122047D0	United Kingdom	D0	2012-02-01
AU2010269978A1	Australia	A1	2012-02-02
SG177380A1	Singapore	A1	2012-02-28
EP2421357A1	European Patent Office (EPO)	A1	2012-02-29
GB201203257D0	United Kingdom	D0	2012-04-11
GB201204592D0	United Kingdom	D0	2012-05-02
GB201205702D0	United Kingdom	D0	2012-05-16
GB201207814D0	United Kingdom	D0	2012-06-13
US2012167237A1	United States of America	A1	2012-06-28
US2012167237A1	United States of America	A1	2012-06-28
GB201208708D0	United Kingdom	D0	2012-07-04
GB201208749D0	United Kingdom	D0	2012-07-04
US2012204278A1	United States of America	A1	2012-08-09
US2012204278A1	United States of America	A1	2012-08-09
CN102638971A	China	A	2012-08-15
GB201211692D0	United Kingdom	D0	2012-08-15
HK1162119A	Hong Kong, China	A	2012-08-24
HK1162119A1	Hong Kong, China	A1	2012-08-24
HK1162119A1	Hong Kong, China	A1	2012-08-24
EP2517556A2	European Patent Office (EPO)	A2	2012-10-31
EP2517557A2	European Patent Office (EPO)	A2	2012-10-31
GB201216795D0	United Kingdom	D0	2012-11-07
JP2012532598A	Japan	A	2012-12-20
EP2421357B1	European Patent Office (EPO)	B1	2013-01-23
SG186238A1	Singapore	A1	2013-01-30
AU2011266843A1	Australia	A1	2013-02-14
US2013042331A2	United States of America	A2	2013-02-14
US2013042331A2	United States of America	A2	2013-02-14
EP2564695A1	European Patent Office (EPO)	A1	2013-03-06
CA2846319A1	Canada	A1	2013-03-28
CA2846322A1	Canada	A1	2013-03-28
WO2013041844A2	World Intellectual Property Organization (WIPO)	A2	2013-03-28
WO2013041845A2	World Intellectual Property Organization (WIPO)	A2	2013-03-28
WO2013041846A2	World Intellectual Property Organization (WIPO)	A2	2013-03-28
AU2011266843A2	Australia	A2	2013-04-11
DK2421357T3	Denmark	T3	2013-04-15
PT2421357E	Portugal	E	2013-04-18
HK1172207A	Hong Kong, China	A	2013-04-19
HK1172207A1	Hong Kong, China	A1	2013-04-19
HK1172207A1	Hong Kong, China	A1	2013-04-19
EP2582230A1	European Patent Office (EPO)	A1	2013-04-24
KR20130042461A	Republic of Korea	A	2013-04-26
WO2013061098A2	World Intellectual Property Organization (WIPO)	A2	2013-05-02
ES2403087T3	Spain	T3	2013-05-14
HRP20130253T1	Croatia	T1	2013-05-31
HRP20130253T1	Croatia	T1	2013-05-31
CA2857569A1	Canada	A1	2013-06-06
WO2013079953A1	World Intellectual Property Organization (WIPO)	A1	2013-06-06
EP2604110A2	European Patent Office (EPO)	A2	2013-06-19
EP2604111A2	European Patent Office (EPO)	A2	2013-06-19
WO2013061098A3	World Intellectual Property Organization (WIPO)	A3	2013-06-20
SI2421357T1	Slovenia	T1	2013-06-28
SMT201300046B	San Marino	B	2013-07-09
SMT201300046B	San Marino	B	2013-07-09
WO2013041844A3	World Intellectual Property Organization (WIPO)	A3	2013-07-11
EP2517556A3	European Patent Office (EPO)	A3	2013-07-17
EP2517557A3	European Patent Office (EPO)	A3	2013-07-24
CN103228130A	China	A	2013-07-31
PL2421357T3	Poland	T3	2013-07-31
WO2013041846A3	World Intellectual Property Organization (WIPO)	A3	2013-08-01
WO2013041845A3	World Intellectual Property Organization (WIPO)	A3	2013-08-08
EP2604110A3This record	European Patent Office (EPO)	A3	2013-08-14
US2013243759A1	United States of America	A1	2013-09-19
CA2867530A1	Canada	A1	2013-10-03
US2013263292A1	United States of America	A1	2013-10-03
US2013263293A1	United States of America	A1	2013-10-03
WO2013144566A2	World Intellectual Property Organization (WIPO)	A2	2013-10-03
WO2013144567A1	World Intellectual Property Organization (WIPO)	A1	2013-10-03
EP2649184A1	European Patent Office (EPO)	A1	2013-10-16
HK1180535A	Hong Kong, China	A	2013-10-25
HK1180535A1	Hong Kong, China	A1	2013-10-25
HK1180535A1	Hong Kong, China	A1	2013-10-25
NZ597481A	New Zealand	A	2013-10-25
GB2501753A	United Kingdom	A	2013-11-06
GB2502127A	United Kingdom	A	2013-11-20
WO2013144566A3	World Intellectual Property Organization (WIPO)	A3	2013-11-21
WO2013171505A2	World Intellectual Property Organization (WIPO)	A2	2013-11-21
US2013318643A1	United States of America	A1	2013-11-28
US2013318643A1	United States of America	A1	2013-11-28
EP2604111A3	European Patent Office (EPO)	A3	2013-12-18
WO2013171505A3	World Intellectual Property Organization (WIPO)	A3	2014-01-03
US2014041067A1	United States of America	A1	2014-02-06
HK1185100A	Hong Kong, China	A	2014-02-07
HK1185100A1	Hong Kong, China	A1	2014-02-07
AU2012311286A1	Australia	A1	2014-05-01
AU2012311288A1	Australia	A1	2014-05-01
US2014120582A1	United States of America	A1	2014-05-01
US2014120582A1	United States of America	A1	2014-05-01
AU2012343587A1	Australia	A1	2014-05-15
US2014134156A1	United States of America	A1	2014-05-15
US2014134156A1	United States of America	A1	2014-05-15

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97 legal events, as 12 offices reported them to INPADOC

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Events

Legal events, newest first
	Event	Code	Office
2022-06-01	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2020-05-01	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-11-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-06-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2019-06-19	Translation for ep filed (entry of ep into country)FP	FP	BE
2019-05-22	Patent revokedRevoked27W	27W	EP
2019-05-22	Gb: patent revoked under art. 102 of the ep convention designating the uk as contracting stateRevokedGBPR	GBPR	EP
2019-04-19	Patent revokedRevokedORIGINAL CODE: 0009271RDAG	RDAG	EP
2019-04-19	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: PATENT REVOKEDSTAA	STAA	EP
2019-01-02	Communication despatched that patent is revokedRevokedORIGINAL CODE: EPIDOSNREV1RDAF	RDAF	EP
2019-01-02	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: THE PATENT HAS BEEN GRANTEDSTAA	STAA	EP
2018-11-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-11-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-11-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-11-20	Epo's revocation decision now finalR064	R064	DE
2018-11-20	Patent revoked by epoRevokedR103	R103	DE
2018-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2018-09-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2018-07-26	Fee paymentPLFP	PLFP	FR
2018-06-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2018-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2018-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2018-02-28	Patent ceasedCeasedPL	PL	CH
2018-02-05	Reply of patent proprietor to notice(s) of opposition receivedOppositionORIGINAL CODE: EPIDOSNOBS3PLBB	PLBB	EP
2017-11-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-11-17	Standard patents granted in hong kongGrantedGR	GR	HK
2017-10-04	Opposition filedOpposition26	26	EP
2017-10-04	Notice of opposition and request to file observation + time limit sentOppositionORIGINAL CODE: EPIDOSNOBS2PLAX	PLAX	EP
2017-09-01	Opposition filedOppositionORIGINAL CODE: 0009260PLBI	PLBI	EP
2017-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-08-28	Opposition filed against patentOppositionR026	R026	DE
2017-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-07-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-07-26	Fee paymentPLFP	PLFP	FR
2017-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-04-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-04-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-04-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-04-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-04-15	Deletion acc. to par. 5 (withdrawal of the translation of the ep patent)MK05	MK05	AT
2017-03-27	Invalidated european patentMG4D	MG4D	LT
2017-02-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2017-02-22	Translation for ep filed (entry of ep into country)FP	FP	NL
2017-02-13	Ep patent with danish claimsT3	T3	DK
2017-01-12	Dpma publication of mentioned ep patent grantGrantedR096	R096	DE
2016-12-28	European patents granted designating irelandGrantedFG4D	FG4D	IE
2016-12-15	Reference to at number (ep patent validated in austria)REF	REF	AT
2016-11-30	Divisional application: reference to earlier applicationAC	AC	EP
2016-11-30	Designated contracting statesAK	AK	EP
2016-11-30	European patent takes effect as a national patent in ch/liEP	EP	CH
2016-11-30	European patent grantedGrantedFG4D	FG4D	GB
2016-10-28	(expected) grantORIGINAL CODE: 0009210GRAA	GRAA	EP
2016-10-21	Grant fee paidORIGINAL CODE: EPIDOSNIGR3GRAS	GRAS	EP
2016-09-07	Intention to grant announcedINTG	INTG	EP
2016-08-07	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP	GRAP	EP
2016-08-03	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2016-08-03	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2016-08-03	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2016-08-03	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2016-08-03	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2016-08-03	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2016-06-30	Amendment of ipc main classPREVIOUS MAIN CLASS: A01K0067027000R079	R079	DE
2015-06-03	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2015-06-03	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2015-06-03	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2015-06-03	Information on inventor provided before grant (corrected)RIN1	RIN1	EP
2015-05-27	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2015-05-14	Observations filed by third partiesORIGINAL CODE: EPIDOSNTIPATPAC	TPAC	EP
2014-05-07	First examination report despatched17Q	17Q	EP
2014-04-01	Observations filed by third partiesORIGINAL CODE: EPIDOSNTIPATPAC	TPAC	EP
2014-03-26	Request for examination filed17P	17P	EP
2014-03-26	Designated contracting states (corrected)RBV	RBV	EP
2014-02-07	Requests to designate patent in hong kongDE	DE	HK
2013-08-14	Designated contracting statesAK	AK	EP
2013-08-14	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2013-08-14	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2013-08-14	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2013-08-14	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2013-08-14	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2013-07-12	Search report despatchedORIGINAL CODE: 0009013PUAL	PUAL	EP
2013-06-19	Divisional application: reference to earlier applicationAC	AC	EP
2013-06-19	Designated contracting statesAK	AK	EP
2013-06-18	Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI	PUAI	EP

Animal models and therapeutic molecules

Abstract

Term

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Designated states37