EP2510941A3

Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist

Abstract

The present invention relates to methods for treating multiple sclerosis by administering therapeutically effective amounts of an alpha-fetoprotein polypeptide (or a biologically active fragment, derivative, or analog thereof) and an integrin antagonist (e.g., natalizumab) to a patient in need thereof. Also disclosed are compositions and kits that comprise therapeutically effective amounts of an alpha-fetoprotein polypeptide (or a biologically active fragment, derivative, or analog thereof) and an integrin antagonist (e.g., natalizumab).

Term

Projected expiry 20 February 2028.

Every citation, both ways

Citations
Document	Relation	Office	Category	Cited during	Relevant claims
WO2008079270A2	Cites	World Intellectual Property Organization (WIPO)	E	Search report	1,3-12

9 priority claims, no other members on record

This recordMember, by publication datePriority claim

Priority claims9

Priority claims
Document	Office	Kind	Date
902216P	United States of America	–	2007-02-20
90221607	United States of America	P	2007-02-20
90221607	United States of America	P	2007-02-20
08725824	European Patent Office (EPO)	A	2008-02-20
08725824	European Patent Office (EPO)	A	2008-02-20
08725824	–	–	–
902216P	–	–	–
EP20080725824	–	–	–
US20070902216P	–	–	–

11 legal events, as the office reported them to INPADOC

Over the term

Point at a mark for the event

Events

Legal events, newest first
	Event	Code
2014-01-15	Application deemed to be withdrawnWithdrawn18D	18D
2013-12-13	Information on the status of an ep patent application or granted ep patentGrantedSTAA	STAA
2013-01-23	Designated contracting statesAK	AK
2013-01-23	Information provided on ipc code assigned before grantRIC1	RIC1
2013-01-23	Information provided on ipc code assigned before grantRIC1	RIC1
2013-01-23	Information provided on ipc code assigned before grantRIC1	RIC1
2012-12-21	Search report despatchedPUAL	PUAL
2012-10-17	Request for examination filed17P	17P
2012-10-17	Divisional application: reference to earlier applicationAC	AC
2012-10-17	Designated contracting statesAK	AK
2012-10-16	Public reference made under article 153(3) epc to a published international application that has entered the european phasePUAI	PUAI