Nova Patents
EP1813293A2

Anti-infective medical device and production method

Abstract

Methods of providing and/or maintaining anti-infective activity to a medical device generally comprising exposing the medical device to an anti-infective oxidant and transferring the anti-infective oxidant into a wall of the medical device. One embodiment comprises exposing a medical device which is at least in part within a patient to the anti-infective oxidant. Another embodiment comprises exposing a medical device to an aqueous solution which produces the anti-infective oxidant and transferring a sufficient amount of the anti-infective oxidant into the medical device wall to provide the medical device with anti-infective activity. Another aspect of the invention is directed to an oxidant-releasing member which has the anti-infective oxidant releasably contained therein and which is configured to be disposed adjacent to the medical device. Presently preferred medical devices useful in the method of the invention include catheters such as venous, arterial, and urinary catheters, generally comprising an elongated catheter shaft having a lumen extending therein, and optionally hav ing a balloon on the shaft in fluid communication with the catheter lumen.

EP1813293A2, drawing sheet 1
Sheet 1 of 16

Term

Term ended

Projected expiry passed 2 June 2020, 6.3 years ago.

  1. Priority
  2. Filed
  3. Published
  4. Projected expiry
  5. Today

44 claims: 7 independent, 37 dependent

  1. 1
    A method of providing anti-infective activity to a medical device, comprising a) providing a medical device which is at least in part within a patient;b) exposing the medical device to an anti-infective oxidant;and c) transferring the anti-infective oxidant into a wall of the medical device.
  2. 25
    An anti-infective oxidant-releasing member, comprising an elongated body configured to be slidably disposed within a lumen of a medical device and an anti-infective oxidant releasably contained within the elongated body.
  3. 32
    A method of providing anti-infective activity to a medical device, comprising a) exposing the medical device to a solution which produces an anti-infective oxidant;and b) transferring a sufficient amount of anti-infective oxidant into a wall of the medical device to provide the medical device with anti-infective activity.
  4. 39
    A method of providing anti-infective activity to a medical device, comprising a) exposing an oxidant-releasing member to a formulation which generates an anti-infective oxidant, so that the anti-infective oxidant diffuses into the oxidant-releasing member;and b) exposing the medical device to the oxidant-releasing member so that the anti-infective oxidant diffuses from the oxidant-releasing member into a wall of the medical device.
  5. 40
    An anti-infective medical device having a wall, said device being designed for introduction into the body of a patient, at least a portion of said device, and said wall, being in contact with an anti-infective oxidant.
  6. 41
    A method of dis-infecting a medical device for administration to the body of a patient, said device having a wall, said method comprising a) exposing the medical device in its administered state to an anti-infective oxidant, and b) bringing said oxidant in contact with said wall.
  7. 42
    A method of controlling the microbial growth on a surface of a medical device for administration to the body of a patient, said device having a wall, said method comprising a) exposing the medical device in its administered state to an anti-infective oxidant, and b) bringing said oxidant in contact with said wall.
Independent claims7