EP1599209A4

Inhalation composition

Abstract

The invention provides a dry powder inhalation composition comprising medicament particles and a mixture of lactose particles with a VMD of between about 70 and about 120 microns and a diameter of less than 250 microns, the mixture being characterized in that up to 96% by weight of the lactose particles are less than 150 microns in diameter and wherein up to 25% by weight of the lactose particles are less than 5 microns in diameter. The compositions provide for a more accurate, uniform and consistent dispersion when used with, for example, a multidose dry powder inhaler. Also disclosed are methods for use of the compositions of the invention.

Term

Term ended

Projected expiry passed 21 August 2023, 3.1 years ago.

Every citation, both ways

Citations
Document	Relation	Office	Category	Cited during	Relevant claims
WO0053158A1	Cites	World Intellectual Property Organization (WIPO)	A	Search report	–
US2002106332A1	Cites	United States of America	X	Search report	1-13
US2002110529A1	Cites	United States of America	X	Search report	1-9,12,13
US6017963A	Cites	United States of America	A	Search report	–
WO0053158A	Cites	World Intellectual Property Organization (WIPO)	–	–	–
DMV-FONTERRA EXCIPIENTS: "Pharmatose, milled and sieved lactose.", XP002529164, Retrieved from the Internet <URL:http://www.dmv-fonterra-excipients.com/products/~/media/DBF13799A281431DB94DB5C36CCC48B7.ashx> [retrieved on 20090525]	Non-patent	–	–	Search report	–
XIAN MING ZENG ET AL: "THE INFLUENCE OF LACTOSE CARRIER ON THE CONTENT HOMOGENEITY AND DISPERSIBILITY OF BECLOMETHASONE DIPROPIONATE FROM DRY POWDER AEROSOLS", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 197, no. 1/02, 1 January 2000 (2000-01-01), pages 41 - 52, XP001031575, ISSN: 0378-5173	Non-patent	–	–	Search report	–
CARIUS W: "Process monitoring with High-shear High Intensity Mixers/Power Consumption Measurement in Pilot Plant Laboratory", PHARMAZEUTISCHE INDUSTRIE 1992 DE, vol. 54, no. 6, 1992, pages 543 - 546, XP002529165, ISSN: 0031-711X	Non-patent	–	–	Search report	–

87 members in 21 offices

This recordMember, by publication datePriority claim11 more offices are in the list below

Priority claims5

Priority claims
Document	Office	Kind	Date
0219513	United Kingdom	–	2002-08-21
0219514	United Kingdom	–	2002-08-21
0219513	United Kingdom	A	2002-08-21
0219514	United Kingdom	A	2002-08-21
0326385	United States of America	W	2003-08-21

Members87

Family members, oldest first
Document	Office	Kind
GB0219511D0	United Kingdom	D0	2002-10-02
GB0219512D0	United Kingdom	D0	2002-10-02
GB0219513D0	United Kingdom	D0	2002-10-02
GB0219514D0	United Kingdom	D0	2002-10-02
CA2499273A1	Canada	A1	2004-03-04
CA2499278A1	Canada	A1	2004-03-04
CA2499280A1	Canada	A1	2004-03-04
WO2004017914A2	World Intellectual Property Organization (WIPO)	A2	2004-03-04
WO2004017918A2	World Intellectual Property Organization (WIPO)	A2	2004-03-04
WO2004017942A1	World Intellectual Property Organization (WIPO)	A1	2004-03-04
AU2003258334A1	Australia	A1	2004-03-11
AU2003260049A1	Australia	A1	2004-03-11
AU2003269989A1	Australia	A1	2004-03-11
WO2004017914A3	World Intellectual Property Organization (WIPO)	A3	2004-04-29
WO2004017918A3	World Intellectual Property Organization (WIPO)	A3	2004-05-06
US2004258626A1	United States of America	A1	2004-12-23
MXPA05001901A	Mexico	A	2005-04-28
MXPA05001902A	Mexico	A	2005-04-28
MXPA05001903A	Mexico	A	2005-04-28
NO20051414L	Norway	L	2005-05-20
NO20051461L	Norway	L	2005-05-20
NO20051463L	Norway	L	2005-05-20
EP1545634A2	European Patent Office (EPO)	A2	2005-06-29
WO2004017918A8	World Intellectual Property Organization (WIPO)	A8	2005-06-30
WO2004017918A9	World Intellectual Property Organization (WIPO)	A9	2005-06-30
WO2004017942A8	World Intellectual Property Organization (WIPO)	A8	2005-06-30
WO2004017914A8	World Intellectual Property Organization (WIPO)	A8	2005-07-07
US2005158248A1	United States of America	A1	2005-07-21
EP1560567A1	European Patent Office (EPO)	A1	2005-08-10
KR20050083648A	Republic of Korea	A	2005-08-26
KR20050088276A	Republic of Korea	A	2005-09-05
CN1681536A	China	A	2005-10-12
EP1599209A2	European Patent Office (EPO)	A2	2005-11-30
EA200500387A1	Eurasian Patent Organization (EAPO)	A1	2005-12-29
EA200500388A1	Eurasian Patent Organization (EAPO)	A1	2005-12-29
EA200500389A1	Eurasian Patent Organization (EAPO)	A1	2005-12-29
KR20060052649A	Republic of Korea	A	2006-05-19
ZA200502172B	South Africa	B	2006-05-31
ZA200502176B	South Africa	B	2006-05-31
ZA200502177B	South Africa	B	2006-05-31
JP2006515830A	Japan	A	2006-06-08
JP2006516531A	Japan	A	2006-07-06
JP2006517178A	Japan	A	2006-07-20
EA007374B1	Eurasian Patent Organization (EAPO)	B1	2006-10-27
EA007375B1	Eurasian Patent Organization (EAPO)	B1	2006-10-27
EA007377B1	Eurasian Patent Organization (EAPO)	B1	2006-10-27
NZ538965A	New Zealand	A	2006-11-30
US2006292083A1	United States of America	A1	2006-12-28
NZ538964A	New Zealand	A	2007-03-30
TNSN05046A1	Tunisia	A1	2007-05-14
TNSN05047A1	Tunisia	A1	2007-05-14
TNSN05048A1	Tunisia	A1	2007-05-14
EP1560567A4	European Patent Office (EPO)	A4	2007-08-22
NZ538963A	New Zealand	A	2008-03-28
CN100379405C	China	C	2008-04-09
AU2003258334B2	Australia	B2	2009-03-05
CN101426476A	China	A	2009-05-06
EP1599209A4This record	European Patent Office (EPO)	A4	2009-07-08
EP1545634A4	European Patent Office (EPO)	A4	2009-09-09
AU2003260049B2	Australia	B2	2009-09-10
US2009264389A1	United States of America	A1	2009-10-22
AU2003269989B2	Australia	B2	2009-11-05
AU2003269989B8	Australia	B8	2009-11-12
JP2011063621A	Japan	A	2011-03-31
CA2499273C	Canada	C	2011-06-21
KR101052693B1	Republic of Korea	B1	2011-07-28
JP4744876B2	Japan	B2	2011-08-10
EP1599209B1	European Patent Office (EPO)	B1	2011-08-17
AT520405T	Austria	T	2011-09-15
ATE520405T1	Austria	T1	2011-09-15
US8075873B2	United States of America	B2	2011-12-13
ES2371601T3	Spain	T3	2012-01-05
US2012065175A1	United States of America	A1	2012-03-15
EP1545634B1	European Patent Office (EPO)	B1	2012-08-01
US8273331B2	United States of America	B2	2012-09-25
PT1545634E	Portugal	E	2012-11-14
DK1545634T3	Denmark	T3	2012-11-19
ES2395261T3	Spain	T3	2013-02-11
CA2499278C	Canada	C	2013-03-19
JP2013177429A	Japan	A	2013-09-09
JP5345605B2	Japan	B2	2013-11-20
NO334076B1	Norway	B1	2013-12-02
KR101369631B1	Republic of Korea	B1	2014-03-05
IL167009A	Israel	A	2014-06-30
BRPI0313645A2	Brazil	A2	2017-12-12
BRPI0313764A2	Brazil	A2	2018-11-21
BRPI0313647A2	Brazil	A2	2019-02-19

76 legal events, as 9 offices reported them to INPADOC

Over the term

Point at a mark for the event

Events

Legal events, newest first
	Event	Code	Office
2015-02-19	Publication of grant of european patent rescindedR107	R107	DE
2015-01-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-01-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2015-01-07	Patent revokedRevoked27W	27W	EP
2015-01-07	Gb: patent revoked under art. 102 of the ep convention designating the uk as contracting stateRevokedGBPR	GBPR	EP
2014-12-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-12-15	Patent declared invalid from date of grant onwardsPLX	PLX	CH
2014-12-05	Patent revokedRevokedORIGINAL CODE: 0009271RDAG	RDAG	EP
2014-12-05	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: PATENT REVOKEDSTAA	STAA	EP
2014-11-28	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-11-28	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-11-28	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-11-28	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-10-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2014-08-18	Communication despatched that patent is revokedRevokedORIGINAL CODE: EPIDOSNREV1RDAF	RDAF	EP
2014-06-24	Epo's revocation decision now finalR064	R064	DE
2014-06-24	Patent revoked by epoRevokedR103	R103	DE
2014-02-19	Opposition filed (corrected)OppositionR26	R26	EP
2014-01-17	Opposition data, opponent's data or that of the opponent's representative modifiedOppositionORIGINAL CODE: 0009299OPPOPLAB	PLAB	EP
2013-11-29	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2013-06-28	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2013-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-12-07	Reply of patent proprietor to notice(s) of opposition receivedOppositionORIGINAL CODE: EPIDOSNOBS3PLBB	PLBB	EP
2012-08-16	Opposition filed against patentOppositionR026	R026	DE
2012-06-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-06-28	Filing of the translation of the text of european patentsAG4A	AG4A	HU
2012-06-27	Opposition filedOpposition26	26	EP
2012-06-27	Opposition filedOpposition26	26	EP
2012-06-27	Opposition filedOpposition26	26	EP
2012-06-27	Notice of opposition and request to file observation + time limit sentOppositionORIGINAL CODE: EPIDOSNOBS2PLAX	PLAX	EP
2012-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-05-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-05-25	Opposition filedOppositionORIGINAL CODE: 0009260PLBI	PLBI	EP
2012-04-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-03-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-03-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-02-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-02-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-02-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-02-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-02-15	Deletion acc. to par. 5 (withdrawal of the translation of the ep patent)MK05	MK05	AT
2012-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-01-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2012-01-05	Definitive protectionFG2A	FG2A	ES
2011-11-30	Translation files for an european patent granted for nl, confirming art. 52 par. 1 or 6 of the patents act 1995GrantedT3	T3	NL
2011-10-31	New agentNV	NV	CH
2011-10-20	Dpma publication of mentioned ep patent grantGrantedR096	R096	DE
2011-09-14	European patents granted designating irelandGrantedFG4D	FG4D	IE
2011-08-31	European patent takes effect as a national patent in ch/liEP	EP	CH
2011-08-17	Designated contracting statesAK	AK	EP
2011-08-17	Request for extension of the european patentAX	AX	EP
2011-08-17	European patent grantedGrantedFG4D	FG4D	GB
2011-07-15	(expected) grantORIGINAL CODE: 0009210GRAA	GRAA	EP
2011-07-08	Grant fee paidORIGINAL CODE: EPIDOSNIGR3GRAS	GRAS	EP
2011-03-04	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP	GRAP	EP
2009-09-23	First examination report despatched17Q	17Q	EP
2009-07-08	Supplementary search report drawn up and despatchedA4	A4	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2009-07-08	Information provided on ipc code assigned before grantRIC1	RIC1	EP
2008-01-09	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
2005-12-14	Requested extension states of the european patent have changedRAX	RAX	EP
2005-11-30	Request for examination filed17P	17P	EP
2005-11-30	Designated contracting statesAK	AK	EP
2005-11-30	Request for extension of the european patentAX	AX	EP
2005-10-14	Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI	PUAI	EP

Inhalation composition

Abstract

Term

Priority claims5

Members87

Over the term

Events

Numbers

Titles3

Classification

Designated states28