EP0900568A3
AMPA antagonists for the treatment of dyskinesias associated with dopamine agonist therapy
Abstract
The invention relates to a method of treating dyskinesias associated with dopamine agonist therapy in a mammal which comprises administering to said mammal a compound, as defined herein, which is an antagonist of the AMPA receptor. Dopamine agonist therapy, as referred to in the present invention, is generally used in the treatment of a central nervous system disorder such as Parkinson's disease.
Term
Term ended
Projected expiry passed 4 September 2018, 8.1 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
Every citation, both waysCites: the store holds 6 of 7
| Document | Relation | Office | Category | Cited during | Relevant claims |
|---|---|---|---|---|---|
| US4183931A | Cites | United States of America | A | Search report | 1-7 |
| WO9213535A1 | Cites | World Intellectual Property Organization (WIPO) | A | Search report | 1-7 |
| WO9308173A1 | Cites | World Intellectual Property Organization (WIPO) | A | Search report | 1-7 |
| WO9521842A1 | Cites | World Intellectual Property Organization (WIPO) | A | Search report | 1-7 |
| WO9608493A1 | Cites | World Intellectual Property Organization (WIPO) | A | Search report | 1-7 |
| WO9743276A1 | Cites | World Intellectual Property Organization (WIPO) | DAPA | Search report | 1-7 |
| KOE B K ET AL: "ENHANCEMENT OF BENZODIAZEPINE BINDING BY METHAQUALONE AND RELATED QUINAZOLINONES", DRUG DEVELOPMENT RESEARCH,US,NEW YORK, NY, vol. 7, no. 3, 1986, pages 255 - 268, XP002064447, ISSN: 0272-4391 | Non-patent | – | – | Search report | – |
| LOSCHMANN P. ET AL: "Synergism of the AMPA-Antagonist NBQX and the NMDA-Antagonist CPP with L-Dopa in Models of Parkinson s Disease.", JOURNAL OF NEURAL TRANSMISSION. PARKINSONS DISEASE AND DEMENTIA SECTION., vol. 3, no. 3, 1991, pages 203 - 213, XP000973350 | Non-patent | – | – | Search report | – |
19 members in 10 offices
Priority claims5
| Document | Office | Kind | Date |
|---|---|---|---|
| 58098P | United States of America | – | |
| 5809897 | United States of America | P | |
| 5809897 | United States of America | P | |
| 58098P | – | – | – |
| US19970058098P | – | – | – |
Members19
| Document | Office | Kind | |
|---|---|---|---|
| HU9802021D0 | Hungary | D0 | |
| CA2246839A1 | Canada | A1 | |
| EP0900568A2 | European Patent Office (EPO) | A2 | |
| AU8312098A | Australia | A | |
| IL125950A0 | Israel | A0 | |
| KR19990029570A | Republic of Korea | A | |
| HU9802021A2 | Hungary | A2 | |
| HUP9802021A2 | Hungary | A2 | |
| JPH11158072A | Japan | A | |
| ZA988139B | South Africa | B | |
| NZ331741A | New Zealand | A | |
| US6136812A | United States of America | A | |
| EP0900568A3This record | European Patent Office (EPO) | A3 | |
| HU9802021A3 | Hungary | A3 | |
| HUP9802021A3 | Hungary | A3 | |
| AU736254B2 | Australia | B2 | |
| JP2001316267A | Japan | A | |
| CA2246839C | Canada | C | |
| KR100440659B1 | Republic of Korea | B1 |
15 legal events, as the office reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | |
|---|---|---|
| Application deemed to be withdrawnWithdrawn18D | 18D | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWNSTAA | STAA | |
| Information provided on ipc code assigned before grantRIC1 | RIC1 | |
| Information provided on ipc code assigned before grantRIC1 | RIC1 | |
| Information provided on ipc code assigned before grantRIC1 | RIC1 | |
| Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOSNIGR1GRAP | GRAP | |
| First examination report despatched17Q | 17Q | |
| Designation fees paidAT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SEAKX | AKX | |
| Designated contracting statesAK | AK | |
| Request for extension of the european patentAL;LT;LV;MK;RO;SIAX | AX | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | |
| Request for examination filed17P | 17P | |
| Designated contracting statesAK | AK | |
| Request for extension of the european patentAL;LT;LV;MK;RO;SIAX | AX | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI |
Numbers
- Publication
- 0900568
- Publication, DOCDB
- 0900568
- Publication, EPODOC
- EP0900568
- Application
- 98307181
- Application, DOCDB
- 98307181
- Application, EPODOC
- EP19980307181
Titles3
- German
- AMPA Antagonisten zur Behandlung von motorischen Fehlfunktionen verbunden mit Dopaminagonist Therapie
- English
- AMPA antagonists for the treatment of dyskinesias associated with dopamine agonist therapy
- French
- Antagonistes d'AMPA pour le traitement des dyscinésies associées à la thérapie aux agonistes de la dopamine
Classification
- CPC, 7
- A61K31/505
- A61K31/517
- A61P25/00
- A61P25/14
- A61P25/16
- A61P43/00
- A61K31/44
- IPC, 28
- A61K31 195
- A61K31 198
- A61K31 40
- A61K31 4427
- C07D239 90
- A61K31 4525
- A61K31 505
- A61K31 517
- A61K45 00
- A61P25 00
- A61P25 14
- A61P25 16
- A61P43 00
- C07D239 91
- C07D401 04
- C07D401 06
- C07D401 12
- C07D401 14
- C07D403 04
- C07D403 06
- C07D403 10
- C07D403 12
- C07D405 04
- C07D413 06
- C07D413 14
- C07D417 06
- C07D417 14
- C07D495 04
Designated states2
- Contracting states, 1
- Sweden
- Extension states, 1
- Slovenia