Nova Patents
EP0807434A1

Anti-inflammatory eyedrops

Abstract

Anti-inflammatory eyedrops comprising: (a)0.05 to 0.7 w/v % of diclofenac sodium; (b) 1 to 10 w/v % of γ-cyclodextrin; (c) 1 to 20 w/v % of polyvinylpyrrolidone; and (d) 0.002 to 0.01 w/v % of benzethonium chloride, or 0.002 to 0.005 w/v % of benzalkonium chloride; and having a pH value of 7.0 to 8.5. The eyedrops contain diclofenac sodium at a concentration over a wide range, remain stable for a long period of time, and little irritate the eyes.

Term

Term ended

Projected expiry passed 26 December 2015, 10.7 years ago.

  1. Priority
  2. Filed
  3. Published
  4. Projected expiry
  5. Today

6 claims: 4 independent, 2 dependent

  1. 1
    An anti-inflammatory eye drop comprising (a) 0.05 to 0.7 weight/volume% of diclofenac sodium;(b) 1 to 10 weight/volume% of γ-cyclodextrin;(c) 1 to 20 weight/volume% of polyvinyl pyrrolidone;and (d) 0.002 to 0.01 weight/volume% of benzethonium chloride or 0.002 to 0.005 weight/volume% of benzalkonium chloride, and having a pH value ranging from 7.0 to 8.5.
  2. 4
    The eye drop as set forth in any one of claims 1 to 3 wherein the content of the polyvinyl pyrrolidone ranges from 2 to 10 weight/volume%.
  3. 5
    The eye drop as set forth in any one of claims 1 to 4 wherein the pH value ranges from 7.5 to 8.5.
  4. 6
    The eye drop as set forth in any one of claims 1 to 5 wherein the Fikentscher's K-value of the polyvinyl pyrrolidone ranges from 10 to 95.
Independent claims4