EP0469813A3

Use of zwitterionic compounds and their n-halo derivatives

Abstract

Zwitterionic compounds selected from: taurine (2-aminoethanesulphonic acid), 2(N-morpholino)ethanesulphonic acid (MES), N-(2-acetamido) iminodiacetic acid (ADA), piperazine-N,N′bis(2-ethanesulphonic acid (PIPES), N-(2-acetamido)-2-aminoethanesulphonic acid (ACES), N,N-bis(2-hydroxyethyl)-2-aminoethanesulphonic acid (BES), 3-(N-morpholino)propanesulphonic (MOPS), N-N[tris(hydroxymethyl)-methyl]-2-aminoethanesulphonic acid (TES), N-2-hydroxyethylpiperazine-N′-2-ethanesulphonic acid (HEPES), N-2-hydroxyethylpiperazine-N′3-propanesulphonic acid ((H)EPPS), 2-(cyclohexylamino) ethanesulphonic acid (CHES) or 3-(cyclohexylamino) propanesulphonic acid (CAPS), and their N-halo derivatives can be used separately or in combination in the treatment of related clinical conditions by stimulating myeloperoxidase activity, which in turn stimulates hypochlorous acid production in vivo, which leads inter alia to enhanced leukotriene inactivation.

Term

Term ended

Projected expiry passed 29 July 2011, 15.2 years ago.

Every citation, both ways

Citations
Document	Relation	Office	Category	Cited during
EP0098073A2	Cites	European Patent Office (EPO)	A	Search report
EP0228239A2	Cites	European Patent Office (EPO)	XD	Search report
EP0361908A2	Cites	European Patent Office (EPO)	A	Search report
WO8809657A1	Cites	World Intellectual Property Organization (WIPO)	X	Search report

13 members in 8 offices

This recordMember, by publication datePriority claim

Priority claims4

Priority claims
Document	Office	Kind	Date
274190	Ireland	A	1990-07-30
274190	Ireland	A	1990-07-30
274190	Ireland	–	1990-07-30
IE19900002741	–	–	–

Members13

Family members, oldest first
Document	Office	Kind
CA2048068A1	Canada	A1	1992-01-31
EP0469813A2	European Patent Office (EPO)	A2	1992-02-05
AU8133291A	Australia	A	1992-02-13
EP0469813A3This record	European Patent Office (EPO)	A3	1992-11-19
JPH0597666A	Japan	A	1993-04-20
AU641529B2	Australia	B2	1993-09-23
US5248680A	United States of America	A	1993-09-28
EP0469813B1	European Patent Office (EPO)	B1	1998-12-30
AT175112T	Austria	T	1999-01-15
ATE175112T1	Austria	T1	1999-01-15
DE69130692D1	Germany	D1	1999-02-11
ES2128309T3	Spain	T3	1999-05-16
DE69130692T2	Germany	T2	1999-09-09

48 legal events, as 5 offices reported them to INPADOC

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Events

Legal events, newest first
	Event	Code	Office
2005-07-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2004-10-16	Announcement of lapse in spainLapsedFD2A	FD2A	ES
2004-04-30	Notification of lapseLapsedST	ST	FR
2004-04-01	Nl: lapsed or anulled due to non-payment of the annual feeLapsedNLV4	NLV4	EP
2004-03-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2004-03-17	Gb: european patent ceased through non-payment of renewal feeCeasedGBPC	GBPC	EP
2004-02-03	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2004-02-01	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2003-07-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2003-07-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
2003-01-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2003-01-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2003-01-30	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2003-01-23	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2003-01-22	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
2002-01-01	European patent in force as of 2002-01-01IF02	IF02	GB
1999-12-22	No opposition filedOpposition26N	26N	EP
1999-11-05	No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE	PLBE	EP
1999-11-05	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA	STAA	EP
1999-07-29	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1999-07-15	Patent ceasedCeasedPL	PL	CH
1999-05-16	Definitive protectionFG2A	FG2A	ES
1999-03-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1999-03-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1999-03-26	It: translation for a ep patent filedITF	ITF	EP
1999-03-26	It: translation for a ep patent filedITF	ITF	EP
1999-03-12	Fr: translation filedET	ET	EP
1999-02-11	Corresponds to:REF	REF	EP
1998-12-31	European patent takes effect as a national patent in ch/liEP	EP	CH
1998-12-30	Designated contracting statesAK	AK	EP
1998-12-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1998-12-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1998-12-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1998-12-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1998-12-30	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1998-12-30	Corresponds to:REF	REF	EP
1998-11-13	(expected) grantORIGINAL CODE: 0009210GRAA	GRAA	EP
1998-09-29	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOS IGRAGRAH	GRAH	EP
1998-06-30	Despatch of communication of intention to grantORIGINAL CODE: EPIDOS AGRAGRAG	GRAG	EP
1998-06-30	Despatch of communication of intention to grant a patentORIGINAL CODE: EPIDOS IGRAGRAH	GRAH	EP
1998-03-26	Despatch of communication of intention to grantORIGINAL CODE: EPIDOS AGRAGRAG	GRAG	EP
1995-09-20	First examination report despatched17Q	17Q	EP
1993-06-09	Request for examination filed17P	17P	EP
1993-03-31	Party data changed (applicant data changed or rights of an application transferred)RAP1	RAP1	EP
1992-11-19	Designated contracting statesAK	AK	EP
1992-09-30	Search report despatchedORIGINAL CODE: 0009013PUAL	PUAL	EP
1992-02-05	Designated contracting statesAK	AK	EP
1991-12-18	Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI	PUAI	EP

Use of zwitterionic compounds and their n-halo derivatives

Abstract

Term

Priority claims4

Members13

Over the term

Events

Numbers

Titles3

Classification

Designated states14