EP0378317A3

Microbial transformation product of l-679,934

Abstract

Described is a new immunosuppressant, L-683,519, a monodemethylated rearranged derivative of L-679,934, produced under fermentation conditions utilizing the microorganism, unidentified Actinomycete (Merck Culture Collection MA 6474) ATCC No. 53828. The macrolide immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow and heart transplants.

EP0378317A3, drawing sheet 1 — Sheet 1 of 1

Term

Term ended

Projected expiry passed 5 January 2010, 16.7 years ago.

1 sheet

Sheet 1

Every citation, both ways

Citations
Document	Relation	Office	Category	Cited during
EP0184162A2	Cites	European Patent Office (EPO)	AD	Search report
EP0323042A1	Cites	European Patent Office (EPO)	AP	Search report

7 members in 5 offices

This recordMember, by publication datePriority claim

Priority claims3

Priority claims
Document	Office	Kind	Date
297632	United States of America	–	1989-01-13
29763289	United States of America	A	1989-01-13
US19890297632	–	–	–

Members7

Family members, oldest first
Document	Office	Kind
CA2007678A1	Canada	A1	1990-07-13
EP0378317A2	European Patent Office (EPO)	A2	1990-07-18
JPH02258786A	Japan	A	1990-10-19
EP0378317A3This record	European Patent Office (EPO)	A3	1990-11-28
GB9308204D0	United Kingdom	D0	1993-06-02
GB2266307A	United Kingdom	A	1993-10-27
US5268370A	United States of America	A	1993-12-07

9 legal events, as the office reported them to INPADOC

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Events

Legal events, newest first
	Event	Code
1993-09-22	Application withdrawnWithdrawn18W	18W
1993-09-08	First examination report despatched17Q	17Q
1993-08-05	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: THE APPLICATION HAS BEEN WITHDRAWNSTAA	STAA
1991-06-12	Request for examination filed17P	17P
1990-11-28	Designated contracting statesAK	AK
1990-10-10	Search report despatchedORIGINAL CODE: 0009013PUAL	PUAL
1990-09-21	It: translation for ep claims filedITCL	ITCL
1990-07-18	Designated contracting statesAK	AK
1990-06-02	Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI	PUAI