EP0349429A3

Process for the preparation of dispersible colloidal systems of amphiphilic lipids in the form of submicronic liposomes

Abstract

Process for the preparation of colloidal dispersible systems of amphiphilic lipids, in the form of submicron oligolamellar liposomes, whose wall is constituted by lipids and optionally of a substance A and whose nucleus is constituted by water or an aqueous solution , and optionally containing a substance B, characterized in that: (1) a liquid phase consisting essentially of a solution of the lipids and optionally of the substance A in a solvent or a mixture of solvents is prepared, and may contain the substance B in solution, (2) a second liquid phase consisting essentially of water or an aqueous solution of the substance B is prepared, (3) the first phase is added, with moderate stirring, to the second phase, so as to obtain ,a colloidal suspension of liposomes, (4) if desired, removing all or part of the solvent or mixture of solvents and water, so as to obtain a colloidal suspension of desired concentration of liposomes. Applications: drugs, cosmetics.

Term

Term ended

Projected expiry passed 28 June 2009, 17.2 years ago.

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Every citation, both waysCites: the store holds 3 of 4

Citations
DocumentRelationOfficeCategoryCited during
EP0130577A2CitesEuropean Patent Office (EPO)XSearch report
EP0190050B1CitesEuropean Patent Office (EPO)ASearch report
GB2002319ACitesUnited KingdomXSearch report
STN FILE SUPPLIER (Karlsruhe) & FILE CA & CHEMICAL ABSTRACTS, vol. 102, 1984, no. 138256u, New York, US; L. RYDHAG et al.: "Colloidal stability of liposomes", & SURFACTANTS SOLUTION, ÄPROC. INT. SYMP.Ü, 4TH, MEETING DATE 1982, VOLUME 3, 2039-57Non-patentSearch report