EP0342675A3
Novel quinolonecarboxylic acid derivatives
Abstract
Novel compounds of the present invention are represented by the general formula (I) wherein R₁ is hydrogen atom or amino, R₂ is fluorine atom or methoxy, R₃ is hydrogen atom or a lower alkyl having 1 to 3 carbon atoms, and n is 0 or 1. The compounds of the general formula (1) exhibit higher antibacterial activity with fewer side-effects than known quinolone antibiotics such as ofloxacin and norfloxacin. Further, the compounds having the general formula (1) have reduced phototoxicity which normally accompanies 6,8-difluoroquinoline antibiotics.

Term
Term ended
Projected expiry passed 18 May 2009, 17.4 years ago.
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1 sheet
Sheet 1
Every citation, both ways
| Document | Relation | Office | Category | Cited during |
|---|---|---|---|---|
| EP0230295A2 | Cites | European Patent Office (EPO) | AD | Search report |
| EP0241206A2 | Cites | European Patent Office (EPO) | AD | Search report |
14 members in 9 offices
Priority claims8
| Document | Office | Kind | Date |
|---|---|---|---|
| 12272288 | Japan | – | |
| 12272288 | Japan | A | |
| 12272288 | Japan | A | |
| 31041888 | Japan | – | |
| 31041888 | Japan | A | |
| 31041888 | Japan | A | |
| JP19880122722 | – | – | – |
| JP19880310418 | – | – | – |
Members14
| Document | Office | Kind | |
|---|---|---|---|
| EP0342675A2 | European Patent Office (EPO) | A2 | |
| KR890017243A | Republic of Korea | A | |
| EP0342675A3This record | European Patent Office (EPO) | A3 | |
| JPH0395177A | Japan | A | |
| US5051509A | United States of America | A | |
| JPH0555506B2 | Japan | B2 | |
| KR940000368B1 | Republic of Korea | B1 | |
| EP0342675B1 | European Patent Office (EPO) | B1 | |
| AT117685T | Austria | T | |
| DE68920773D1 | Germany | D1 | |
| DE68920773T2 | Germany | T2 | |
| ES2070142T3 | Spain | T3 | |
| HK151295A | Hong Kong, China | A | |
| CA1340285C | Canada | C |
38 legal events, as 4 offices reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | Office | |
|---|---|---|---|
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Announcement of lapse in spainLapsedFD2A | FD2A | ES | |
| Se: european patent has lapsedLapsedEUG | EUG | EP | |
| Nl: ceased due to reaching the maximum lifetime of a patentCeasedNLV7 | NLV7 | EP | |
| Patent expired after termination of 20 yearsExpiredPE20 | PE20 | GB | |
| Be: patent expiredExpiredBE20 | BE20 | EP | |
| Patent ceasedCeasedPL | PL | CH | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Name/firm changedPFA | PFA | CH | |
| European patent in force as of 2002-01-01IF02 | IF02 | GB | |
| No opposition filedOpposition26N | 26N | EP | |
| No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE | PLBE | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Definitive protectionFG2A | FG2A | ES | |
| Fr: translation filedET | ET | EP | |
| Corresponds to:REF | REF | EP | |
| Designated contracting statesAK | AK | EP | |
| Corresponds to:REF | REF | EP | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| First examination report despatched17Q | 17Q | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Designated contracting statesAK | AK | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 0342675
- Publication, DOCDB
- 0342675
- Publication, EPODOC
- EP0342675
- Application
- 108963
- Application, DOCDB
- 89108963
- Application, EPODOC
- EP19890108963
Titles3
- German
- Chinoloncarbonsäure-Derivate
- English
- Novel quinolonecarboxylic acid derivatives
- French
- Dérivés de l'acide quinolonecarboxylique
Classification
- CPC, 2
- C07D401/04
- A61P31/04
- IPC, 4
- C07D401 14
- A61K31 47
- A61P31 04
- C07D401 04
Designated states1
- Contracting states, 1
- Sweden