EP0206567A3
Compounds of formula û1,1'-biphenyl¨-2-carboxylic acid, 2'-ûûû(substituted)phenyl¨-(substituted)amino¨carbonyl¨-, pharmaceutical compositions comprising the compounds, and a process for preparing the compounds
Abstract
The present invention provides various novel diphenic acid monoamide compounds of the formula Also provided are novel pharmaceutical compositions comprising . the compounds and novel methods for synthesising the compounds. The novel diphenic acid monoamides of the present invention areleukotriene antagonists, 5-lipoxygenase inhibitors, and mediator release inhibitors providing activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and immunoinflammatory conditions.
Term
Term ended
Projected expiry passed 2 June 2006, 20.3 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
1 sheet
Sheet 1
Every citation, both ways
| Document | Relation | Office | Category | Cited during |
|---|---|---|---|---|
| US3995045A | Cites | United States of America | YD | Search report |
17 members in 10 offices
Priority claims10
| Document | Office | Kind | Date |
|---|---|---|---|
| 740799 | United States of America | – | |
| 74079985 | United States of America | A | |
| 74079985 | United States of America | A | |
| 845704 | United States of America | – | |
| 84570486 | United States of America | A | |
| 84570486 | United States of America | A | |
| 740799 | – | – | – |
| 845704 | – | – | – |
| US19850740799 | – | – | – |
| US19860845704 | – | – | – |
Members17
| Document | Office | Kind | |
|---|---|---|---|
| DK258686D0 | Denmark | D0 | |
| US4602023A | United States of America | A | |
| DK258686A | Denmark | A | |
| AU5788886A | Australia | A | |
| EP0206567A2 | European Patent Office (EPO) | A2 | |
| JPS6230750A | Japan | A | |
| ES555673A0 | Spain | A0 | |
| ES8800890A1 | Spain | A1 | |
| ZA863769B | South Africa | B | |
| EP0206567A3This record | European Patent Office (EPO) | A3 | |
| US4786755A | United States of America | A | |
| CA1274240A | Canada | A | |
| AU603986B2 | Australia | B2 | |
| EP0206567B1 | European Patent Office (EPO) | B1 | |
| AT60050T | Austria | T | |
| ATE60050T1 | Austria | T1 | |
| DE3676883D1 | Germany | D1 |
30 legal events, as 2 offices reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | Office | |
|---|---|---|---|
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Patent ceasedCeasedPL | PL | CH | |
| Gb: european patent ceased through non-payment of renewal feeCeasedGBPC | GBPC | EP | |
| No opposition filedOpposition26N | 26N | EP | |
| No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE | PLBE | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents actLapsedNLV1 | NLV1 | EP | |
| Fr: translation not filedEN | EN | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Corresponds to:REF | REF | EP | |
| Designated contracting statesAK | AK | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Corresponds to:REF | REF | EP | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| First examination report despatched17Q | 17Q | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Designated contracting statesAK | AK | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 0206567
- Publication, DOCDB
- 0206567
- Publication, EPODOC
- EP0206567
- Application
- 86304168
- Application, DOCDB
- 86304168
- Application, EPODOC
- EP19860304168
Titles3
- English
- Compounds of formula [1,1'-biphenyl]-2-carboxylic acid, 2'-[[[(substituted)phenyl]-(substituted)amino]carbonyl]-, pharmaceutical compositions comprising the compounds, and a process for preparing the compounds
- French
- Composés de formule acide [1,1'-biphényl]-2-carboxylique, 2'-[[[phényl(substitué)]-amino(substitué)]carbonyl], compositions pharmaceutiques contenant ces composés et un procédé pour la préparation de ces composés
- German
- Verbindungen der Formel 2'-[[[(substituiertes) Phenyl]-(substituiertes) Amino]carbonyl]-[1,1'-biphenyl]-2-Carbonsäure, diese Verbindungen enthaltende pharmazeutische Zusammensetzungen und ein Verfahren zur Herstellung dieser Verbindungen
Classification
- CPC, 7
- C07D207/325
- C07C233/65
- C07D211/26
- C07D213/40
- C07D307/52
- C07D317/54
- C07D319/08
- IPC, 8
- C07C233 65
- C07D207 32
- C07D207 325
- C07D211 26
- C07D213 40
- C07D307 52
- C07D317 54
- C07D319 08
Designated states11
- Contracting states, 11
- Austria
- Belgium
- Switzerland
- Germany
- France
- United Kingdom
- Italy
- Liechtenstein
- Luxembourg
- Netherlands (Kingdom of the)
- Sweden