EP0188084A3

Method for the production of bead dextran materials for gel chromatography

Abstract

The invention pertains to a method for the production of bead dextran materials for gel chromatography. The subject of the invention is a method for the production of bead dextran materials for gel chromatography, wherein dextran is, before or during the suspension process or in both stages, subjected to reduction in an alkaline solution, advantageously by the action of sodium borohydride, whereas the density of crosslinking is controlled above all by variation of the concentration of the initial dextran solution and the resulting gel may be optionally subjected to the additional crosslinking in a separate subsequent operation. The procedure according to the invention provides the product of higher quality with a lower content of carboxylic groups and substantially facilitates the preparation of gels with a very high and a very low crosslink density.

Term

Term ended

Projected expiry passed 4 December 2005, 20.8 years ago.

Every citation, both waysCites: the store holds 2 of 3

Citations
Document	Relation	Office	Category	Cited during
EP0153910A1	Cites	European Patent Office (EPO)	YP	Search report
US3042667A	Cites	United States of America	X	Search report
CHEMICAL ABSTRACTS, vol.94, nr.23, June 8, 1981, page 264, ref.nr. 187905e, Columbus, ohio, US; B. LONNERDAL: "Chemical modification of dextran gels for gel filtration off trace element ligands" & TRACE ELEM. ANAL. CHEM. MED. BIOL., PROC. INT. WORKSHOP, 1st 1980, 439-46	Non-patent	–	–	Search report

9 members in 7 offices

This recordMember, by publication datePriority claim

Priority claims4

Priority claims
Document	Office	Kind	Date
1060984	Czechoslovakia (until 1993)	A	1984-12-29
1060984	Czechoslovakia (until 1993)	–	1984-12-29
1060984	–	–	–
CS19840010609	–	–	–

Members9

Family members, oldest first
Document	Office	Kind
EP0188084A2	European Patent Office (EPO)	A2	1986-07-23
JPS61193068A	Japan	A	1986-08-27
EP0188084A3This record	European Patent Office (EPO)	A3	1986-11-26
CS249368B1	Czechoslovakia (until 1993)	B1	1987-03-12
DD261297A3	German Democratic Republic (until 1990)	A3	1988-10-26
US4794177A	United States of America	A	1988-12-27
EP0188084B1	European Patent Office (EPO)	B1	1989-02-22
DE3568336D1	Germany	D1	1989-03-30
CA1263379A	Canada	A	1989-11-28

35 legal events, as 4 offices reported them to INPADOC

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Events

Legal events, newest first
	Event	Code	Office
1995-01-31	Se: european patent has lapsedLapsedEUG	EUG	EP
1992-10-30	Notification of lapseLapsedST	ST	FR
1992-09-01	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1992-08-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1992-08-17	Nl: lapsed or anulled due to non-payment of the annual feeLapsedNLV4	NLV4	EP
1992-07-01	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1991-12-05	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1991-08-30	Patent ceasedCeasedPL	PL	CH
1991-07-03	Application refused (sect. 28/1977) [restoration of lapsed patent]Lapsed728R	728R	GB
1991-01-23	Application made for restoration (sect. 28/1977)728C	728C	GB
1991-01-07	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
1990-12-31	It: last paid annual feeITTA	ITTA	EP
1990-12-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1990-12-31	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1990-12-31	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
1990-12-03	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
1990-11-29	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
1990-08-01	Gb: european patent ceased through non-payment of renewal feeCeasedGBPC	GBPC	EP
1990-03-07	Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP	PGFP	EP
1990-02-07	No opposition filedOpposition26N	26N	EP
1989-12-22	No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE	PLBE	EP
1989-12-22	Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA	STAA	EP
1989-12-04	Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25	PG25	EP
1989-04-28	Fr: translation filedET	ET	EP
1989-03-30	Corresponds to:REF	REF	EP
1989-03-13	It: translation for a ep patent filedITF	ITF	EP
1989-03-13	It: translation for a ep patent filedITF	ITF	EP
1989-02-22	Designated contracting statesAK	AK	EP
1989-01-07	(expected) grantORIGINAL CODE: 0009210GRAA	GRAA	EP
1988-04-20	First examination report despatched17Q	17Q	EP
1987-04-01	Request for examination filed17P	17P	EP
1986-11-26	Designated contracting statesAK	AK	EP
1986-10-08	Search report despatchedORIGINAL CODE: 0009013PUAL	PUAL	EP
1986-07-23	Designated contracting statesAK	AK	EP
1986-06-07	Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI	PUAI	EP

Method for the production of bead dextran materials for gel chromatography

Abstract

Term

Priority claims4

Members9

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Titles3

Classification

Designated states1