Nova Patents
EP0154884A3

Nucleic acid-protein conjugate

Abstract

@ A protein is covalently coupled to at least one end of a nucleic acid which carries several labels. In an assay the protein will specifically recognize some component of a test system; in an immunoassay the protein can be Protein A which will recognize the Fc portion of IgG which is bound to an unknown antigen if present in the test sample.

Term

Term ended

Projected expiry passed 27 February 2005, 21.6 years ago.

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Every citation, both waysCites: the store holds 6 of 7

Citations
DocumentRelationOfficeCategoryCited during
EP0131830A1CitesEuropean Patent Office (EPO)XPSearch report
GB2019408ACitesUnited KingdomXSearch report
GB2125964ACitesUnited KingdomXPSearch report
US4358535ACitesUnited States of AmericaXSearch report
US4587044ACitesUnited States of AmericaXPSearch report
WO8403520A1CitesWorld Intellectual Property Organization (WIPO)XPSearch report
CHEMICAL ABSTRACTS, vol. 88, 1978, page 219, no. 132899b, Columbus, Ohio, US; M. KROEGER et al.: "Nucleophilic substitution at C-2 of S-alkylated 2-thiocytidines by cysteine and lysine. A new method for specific covalent linking of peptides to nucleic acids" & BIOORG. CHEM. 1977, 6(4), 431-41Non-patent––Search report
CHEMICAL ABSTRACTS, vol. 93, 1980, page 399, no. 64767h, Columbus, Ohio, US; Y.-C. TSE et al.: "Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA" & J. BIOL. CHEM. 1980, 255(12), 5560-5Non-patent––Search report
CHEMICAL ABSTRACTS, vol. 98, 1983, page 229, no. 157399h, Columbus, Ohio, US; S. CHENG et al.: "A versatile method for the coupling of protein to DNA: synthesis of a2-macroglobulin-DNA conjugates" & NUCLEIC ACIDS RES. 1983, 11(3), 659-69Non-patent––Search report