EP0052575A3
Microbubble precursors and methods for their production and use
Abstract
Microbubbles are formed in a liquid, e.g., blood in order to alter the transmission characteristics thereof to electromagnetic and sonic waves transmitted therethrough, by dissolving therein a solid particulate material, preferably as a suspension in a carrier liquid in which the particulate material is at least temporarily stable, the particles of which are substantially free of microbubbles and have a plurality of gas-filled voids communicating with the surface of the particles and providing nuclei for microbubble formation and the ratio of the mass of the particles to the volume of gas in the voids is sufficient to render the liquid in which the particulate material is dissolved supersaturated with respect to the gas in the voids in the area of the liquid surrounding the microbubbles when they are formed.
Term
Term ended
Projected expiry passed 17 November 2001, 24.9 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
Every citation, both ways
| Document | Relation | Office | Category | Cited during |
|---|---|---|---|---|
| US3012893A | Cites | United States of America | A | Search report |
| US3640271A | Cites | United States of America | A | Search report |
| US4265251A | Cites | United States of America | T | Search report |
| WO8002365A1 | Cites | World Intellectual Property Organization (WIPO) | A | Search report |
| IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, vol. BME-24, no. 2, March 1977, pages 107-110, New York, U.S.A. | Non-patent | – | – | Search report |
21 members in 10 offices; this record represents the family
Priority claims2
| Document | Office | Kind | Date |
|---|---|---|---|
| 207741 | United States of America | – | |
| 20774180 | United States of America | A |
Members21
| Document | Office | Kind | |
|---|---|---|---|
| EP0052575A2 | European Patent Office (EPO) | A2 | |
| WO8201642A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU7931382A | Australia | A | |
| EP0052575A3This record | European Patent Office (EPO) | A3 | |
| NO822469L | Norway | L | |
| JPS58500392A | Japan | A | |
| US4442843A | United States of America | A | |
| CA1170569A | Canada | A | |
| AU545866B2 | Australia | B2 | |
| AU4127485A | Australia | A | |
| EP0052575B1 | European Patent Office (EPO) | B1 | |
| AT17311T | Austria | T | |
| ATE17311T1 | Austria | T1 | |
| DE3173476D1 | Germany | D1 | |
| US4657756A | United States of America | A | |
| US4681119A | United States of America | A | |
| AU565842B2 | Australia | B2 | |
| JPS6344731B2 | Japan | B2 | |
| NO163654B | Norway | B | |
| NO163654C | Norway | C | |
| NL960008I1 | Netherlands (Kingdom of the) | I1 |
64 legal events, as 8 offices reported them to INPADOC
Over the term
Point at a mark for the eventEvents
| Event | Code | Office | |
|---|---|---|---|
| Supplementary protection certificate deletionSPCL | SPCL | CH | |
| Supplementary protection certificate expiredExpiredSPCE | SPCE | GB | |
| Expiry of a supplementary protection certificateCCRE | CCRE | BE | |
| Cancelled due to lapse of timeLapsedEELA | EELA | AT | |
| Nl: ceased due to reaching the maximum lifetime of a patentCeasedNLV7 | NLV7 | EP | |
| Patent ceasedCeasedPL | PL | CH | |
| Supplementary protection certificate entered into forceGBCTFESPC/GB96/015: 20011117, EXPIRES: 20051106CTFE | CTFE | GB | |
| Patent expired after termination of 20 yearsExpiredPE20 | PE20 | GB | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Lapsed in a contracting state [announced via postgrant information from national office to epo]LapsedPG25 | PG25 | EP | |
| Be: patent expiredExpired20011117 *SCHERING A.G.BE20 | BE20 | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Annual fee paid to national office [announced via postgrant information from national office to epo]GrantedPGFP | PGFP | EP | |
| Further communications concerning applications for a supplementary protection certificateNLBC1 960008BC1 | BC1 | NL | |
| Supplementary protection certificate grantedGrantedOICM 52675/19950209, 19960223, EXPIRES:20061116SPCG | SPCG | CH | |
| Supplementary protection certificate grantedGranted9490136, 940128, EXPIRES: 20061117SPCG | SPCG | SE | |
| Grant for a certificate of protection (e-series)EEZF | EEZF | AT | |
| Supplementary protection certificate grantedGrantedGBCTFGSPC/GB96/015, 960927, EXPIRES:20051106CTFG | CTFG | GB | |
| Be: grant of a complementary protection certificate095C0014, EXPIRES:20051107CCPV | CCPV | EP | |
| Application for a supplementary protection certificateNLAC1 960008, 960426AC1 | AC1 | NL | |
| Supplementary protection certificate filedGBCTFFSPC/GB96/015, 960521CTFF | CTFF | GB | |
| Supplementary protection certificate filedCHSPCFOICM 52675/950209, 960223SPCF | SPCF | CH | |
| Supplementary protection certificate grantedGranted9490136, 940128, EXPIRES: 20051106SPCG | SPCG | SE | |
| Be: application for a complementary protection certificate095C0014CCPA | CCPA | EP | |
| Application filed for a certificate of protection (e-series)ESZA | ESZA | AT | |
| Se: european patent in force in swedenEAL | EAL | EP | |
| Supplementary certificate of protection granted (eec regulation of 18 june 1992)GrantedFRCY 93C0025, 930624, EXPIRES:20051107CY | CY | FR | |
| Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)FRCR 93C0025 930624CR | CR | FR | |
| Application for supplementary protection certificate filed81730118SPCF | SPCF | SE | |
| It: supplementary protection certificate for pharmaceutical products: grantedGrantedCCP 455, 19930701; SCHERING AKTIENGESELLSCHAFTMEDD | MEDD | EP | |
| Supplementary protection certificate (spc) filedCP | CP | FR | |
| Request for supplementary protection certificate laid open to the public (eec regulation of 18 june 1992)FRCR 93C0025, 930624CR | CR | FR | |
| Lu: last paid annual feeEPTA | EPTA | EP | |
| Supplementary protection certificate (spc) filedCP | CP | FR | |
| It: last paid annual feeITTA | ITTA | EP | |
| No opposition filedOpposition26N | 26N | EP | |
| No opposition filed within time limitOppositionORIGINAL CODE: 0009261PLBE | PLBE | EP | |
| Information on the status of an ep patent application or granted ep patentGrantedSTATUS: NO OPPOSITION FILED WITHIN TIME LIMITSTAA | STAA | EP | |
| Publication of translation of european patent specificationUEP | UEP | AT | |
| Fr: translation filedET | ET | EP | |
| Corresponds to:REF | REF | EP | |
| Designated contracting statesAK | AK | EP | |
| Corresponds to:REF | REF | EP | |
| (expected) grantORIGINAL CODE: 0009210GRAA | GRAA | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| It: translation for a ep patent filedITF | ITF | EP | |
| Party data changed (applicant data changed or rights of an application transferred)RAP1 | RAP1 | EP | |
| Designated contracting statesAK | AK | EP | |
| Request for examination filed17P | 17P | EP | |
| Designated contracting statesAK | AK | EP | |
| Search report despatchedORIGINAL CODE: 0009013PUAL | PUAL | EP | |
| Public reference made under article 153(3) epc to a published international application that has entered the european phaseORIGINAL CODE: 0009012PUAI | PUAI | EP |
Numbers
- Publication
- 0052575
- Application
- 81730118
Titles3
- English
- Microbubble precursors and methods for their production and use
- French
- Microbulles précurseurs et procédés pour leur production et leur utilisation
- German
- Mikroblasendiagnostiziergeräte und Verfahren zu deren Herstellung und Verwendung
Classification
- CPC, 3
- A61K49/223
- A61B8/06
- A61B8/481
- IPC, 10
- A61B5 02
- A61B8 00
- A61B8 06
- A61B10 00
- A61K49 22
- G01N
- G01N1 28
- G01N29 00
- G01N33 15
- G01N33 483
Designated states11
- Contracting states, 11
- Austria
- Belgium
- Switzerland
- Germany
- France
- United Kingdom
- Italy
- Liechtenstein
- Luxembourg
- Netherlands (Kingdom of the)
- Sweden