Implantable chip for medical bio-potential storage and percutaneous read-out

The invention relates to implantable patient chips according to the preamble of claim 1.

(A) In life-threatening conditions of any hospital and cause ent divorce often seconds on the continued success of the treatment. In such cases it is extremely important the erstbehandelnden means all contributing to the history of patient ' tendaten to make it accessible. Due to the complexity of modern medicine and the advanced treatment methods, the contributing to the careful history Data packet often include large amounts of data. This applies particularly to such patient ' side groups to which delivered well-dosed medicines with chronic diseases, leads get. Even with the growing population of Arts executive boards are a Variety of crucial data in medical emergency required. currently exi stare completely differente systems of patient-related data archiving. It is usual z. B. a Nothilfepaß paper. On this are often out of the blood and possibly an underlying disease, no further information on risk factors noted. Au SSSR passport are a variety of other emergency cards partially on paper or Film partly as a non-standard smart card-information system on the market. In The publication DE 42 13 797 a Medical Information System of letztge called described type.

(B) In modern society enter new date in this kind not be known medical conditions or procedure of sessions. One of the major diseases of modern There are diseases related to the cardiovascular system. For evaluation a critical or emergency state, it is for the physician often of decisive Meaning, the time course of such process variables, such as heart rate, blood pressure, Knowing blood glucose or oxygen before the event. currently, who the purpose routinely portable devices used on the body or in the the Pati ducks placed sensors to record temporal profiles of biopotentials that later be evaluated. The object of these devices is usually not aligned to emergencies. They are used in medical diagnostics or research. It would be desirable to have a spatially small device on or in the body of a human being who on not affected due to their size, the "normal" life, and the above-described has feature of continuous storage of biopotentials. In the document DE 43 41 903 describes an implantable telemetric endosystem which Biosignals derives makes percutaneously receivable and evaluated. The spatial size this system is the requirement for minimizing by also. However, a continuous intracorporeal storage not provided.

The object of the invention is to provide an implantable chip, the rou the tinemäßige storing and reading data allowed percutaneously, and about Inappropriate Sensors biopotentials derive and store can.

The invention is an implantable patient {} chip according to the On claim 1 dissolved. Advantageous developments of the invention are the subject of Un dependent claims.

According to the invention, moderate idea is the required electronic circuit minimized and made up, that it can be implanted easily. The räumli che size of {Implantable patient chips} is an estimated 5 × 5 × 1 mm³ not exceed. If the site of implantation, for example, the in<b>Fig.</b> 5 Marked selected region of the upper arm, no special surgical operation skills required, since the implant due to its small size by means of a short section of skin is located subcutaneously. For wound closure is often only a conventional "pull plaster" required. The biocompatible packaging implants part of the state of the technique. Due to its design, the {implantable patient chip} via many years are left in place. An exchange makes only faulty func on which will be very rare in the current state of the art required. at routine mass application of the invention may also be a moderate idea implant tationsgerät comparable come about with a vaccination gun for application.

The basic idea of ​​the invention is, all important medically relevant data always and to have available at all times, regardless of the actual place, the entrained Objects and the personal physical condition. Technically, this is only by the current state of microelectronics possible. The {implantable patient chip} is in its use as a data memory operatively connected to a contact IC map comparable. Uploading and downloading of information is carried out by telemetry. The Method of modern telemetry are sophisticated and miniaturized.

Chip side, the telemetric system is an electronic circuit (<b>4</b>) as an antenna (<b>9</b>) Realized. The present methods allow percutaneously distances of 5 , , , 10 cm wirelessly overcome. To send and receive data as well as Programming the chips used telemetry adapter (<b>13</b>) Of various technologies in Cooperation with a computerized information system (see FIG. <b>Fig.</b> 6).

Important is the issue of data security. This calls for two states to be divorce. On one hand, a "normal" case. The patient is in full possession of his mental powers. It is no accident oa. The access to the data on the chip is only possible when the password stored on the chip with an inputted matches. Unlike in case of an emergency. Here the patient is often not responsive. In the sem second case is subject to the access to the stored data of the medical welding gepflicht. This is achieved by a Master Password Technically, knowledge of basic addition and without exception of medical confidentiality is subject. The localization of the Memory in the patient's body also provides maximum access security ge compared unauthorized. In addition, the inventive concept provides great security for the support because he has all important data always physically with him.

In the preferred embodiment of the invention there is also the task of the Power the integrated units, processor, memory, telemetry unit and biosensing microsystems secure. This object is preferred by withdrawal of electromagnetic energy from a surrounding electrical Alternating field solved. The integrated circuit of the telemetry unit accepts this on administration in conjunction with the antenna (<b>9</b>). The supply of a feeding alternating electric field via the telemetry adapter (<b>13</b>). In metropolitan areas According to the invention provides further on, the existing large area called. "Electrical smog" for the energy supply of the {implantable patient chip} to use.

For storing important medical emergency data erfahrungsge according to storage capacity required by 30 Kbytes. In the preferred embodiment the invention will be used in the present invention store much larger capacity. This has the advantage that for a thorough anamnestic information, risk factors, Drug tolerability. , ., Possibly final radiographs, pump setting (z. B. stored in implanted drug pumps) or / and treatment indications who the can. On the other hand, these capacities are according to the invention also neces dig for the integrated depending on the specification biosensing microsystems which inventions have training in accordance with a cyclic memory mechanism.

Biosensing microsystems (<b>5</b>), (<b>6</b>) According to the invention have the preferred Task derive biopotentials in the body of the patient, evaluate and spei Chern. Mikrosensorisch are at the present state of the art a variety of large SSEN representable: temperatures, pressures, optical values, electric potentials, etc. inven it is preferred according to realized that the biosensors on the Au are ßenhaut of {Implantable patient chips} and there for different Measurement tasks more technically different sensors are able. Direct to Brin supply to the outer skin of the invention has the advantage that no intracorporeal "Wiring" required. Another advantage of the invention is, that a einzusetzender for measuring tasks chip, an inventive implantable { Diagnostic Chip} placed directly to the place of monitoring due to its smallness can be. This can be a body cavity, a bone, an implant, a tissue, in trakraniell, etc.. According to the biopotentials are temporally continuously ge measure, evaluate and continuously written to memory. The memory is this ie as so-called organized. stack, as long as the data is written into the memory until it is full. The next measurement "pushes" any other one position further. This creates a very large period of time can be detected. This can according to measurement task dates be weeks or months.

The preferred embodiment of the invention with a biosensing microsystems the use thereof as a heart rate counter. This object is achieved with subcutaneous Ap plication, where in most areas of the body. This insert has in addition to the {Implantable patient chip} as data storage in addition the advantage that the heart frequency will be saved automatically and continuously and in an emergency or when the body union complaints the doctors available. Also for forensic Mediin produced according to the invention, an advantage in the case of unclear diagnosis of Art "Heart failure".

Another feature of the invention is that the {implantable patient chip} externa ßerlich i. p of the patient's body without technical equipment can not be localized. in the However, emergency of the second case (see above) is the exact localization using the Teleme industry adapters using an electronic circuit for evaluating the electromag netic field strength change determinable.

According to the invention other than the medical data of the patient any Type of data in the memory of the implantable {patients chip} are introduced. This has also advantage for such an important personal documents such. As a Testa ment or personal identification data.

The preferred technical embodiment of the invention according to the <b>Fig.</b> 1 to 6 also has the advantage that it is technologically feasible cost. All technical Methods are known and have a high level.

<b>Fig.</b> 1:(<b>1</b>) Electronic storage unit based on semiconductors.(<b>2</b>) Processor unit to control all on-chip operations, in particular the entry and Reading information via the telemetry unit (<b>4</b>) And the recording, Save and evaluation of biological potentials which biosensing with a micro system (<b>6</b>) Are detected.(<b>3</b>) Electronic circuit for generating and delivering of the modules (<b>1</b>) to (<b>5</b>) necessary operating voltage and currents.(<b>4</b>) Telemetry unit, which in cooperation with the antenna (<b>9</b>) Wireless Data exchange and, depending on the specification, the power supply allows percutaneously.

<b>Fig.</b> 2:(<b>5</b>) Biosensing microsystems (BSMS). An electronic circuit, which in to sammenwirken with biosensors (<b>6</b>) Obtaining medically significant Variables implemented and an internal bus system (<b>7</b>) To the partial devices Pro processor, memory and power supply (<b>1</b>), (<b>2</b>), (<b>3</b>) Is coupled.(<b>6</b>) Biosensors. Part of device (<b>15</b>) Formed at the periphery of the {Implantable Patient chip} (<b>15</b>are) attached to.(<b>7</b>) Internal bus system. Connects the biosensor microsystems (<b>5</b>) To the Teilvorrich tions processor, memory and power supply (<b>1</b>), (<b>2</b>), (<b>3</b>).

<b>Fig.</b> 3:(<b>8th</b>) Skin, organ or body tissue.(<b>9</b>) Antenna. Part of device (<b>4</b>). Used to receive and the emission of elec magnetic waves as carriers of information and / or energy for Betrei ben the partial devices (<b>1</b>) - (<b>5</b>).(<b>10</b>) Material for embedding the part of devices (<b>15</b>).(<b>11</b>) Substrate support. Registers the component devices (<b>1</b>) - (<b>5</b>).

<b>Fig.</b> 4:<b>Fig.</b> 4 contains all part of devices <b>Fig.</b> 3. In addition, a possible localization a biosensor microsystem (<b>6</b>) Shown.

<b>Fig.</b> 5:(<b>12</b>) Possible Sites for subcutaneous implantation of {Implantable patient chips} for use as a medical data storage.

<b>Fig.</b> 6:(<b>13</b>) Device, which in conjunction with (<b>14</b>) For percutaneous Reading, Spei Chern, programming and depending on the specification for supplying energy for the {Implantable patient chip} (<b>15</b>) Is used.(<b>14</b>) Device, most likely a computer system in cooperation with the pre direction (<b>13</b>) The handling of the {implantable patient chip} (<b>15</b>) Allows. The GE advises may fixed -. eg for hospitals - or mobile -. eg for emergency vehicles - out its forms.(<b>15</b>) In the body implantable device {implantable patient chip} to Spoke tion of data and / or the acquisition and processing of medical variables.