Skin decontaminant against chemical skin and nerve warfare agents, comprises a silicone-based emulsion of chloramine, alkaline oxime salt and emulsifiers, and a separate acid glycerol-based dispersion containing diacetyl monoxime

The invention relates to a skin detoxifying agent against skin and Nervenkampfstof fe. Furthermore, the invention relates to an applicator for applying the Hautentgif processing means.

Skin detoxifier are personal equipment of a soldier. they serve the soldiers to be in contact with skin with a skin or nerve To detoxify, fight substance. From a paper (title: Reactive skin decontami nant lotion, Magazine: Today science tomorrow defense, page 36-44, published on 01.01.1994, author: J. Carfield Purdon) is a modern skin detoxifier known. This skin detoxification agent comprising a single composition, the the only active substance contains a diacetyl-salt. The skin detoxifier works well for simple nerve agents. Notes on skin detoxifier can also be found on the Internet at http: //www.odel.on. ca / RSDL / 500ml.html (29.11.1999, 17:29).

The invention has the object of providing a skin detoxifying agent for skin and to devise nerve agents, which quickly against all chemical warfare substances acts whose constituents are chemically stable in condition of storage at simple application to respond quickly and relatively harmless to Users are. For a comprehensive action is an independently expiring pH gradient mixture of detoxification on the skin is important. Another Task is to form a suitable applicator without special Knowledge of the user to quickly find the right application and thus a effective, ie, detoxifying preparation on the skin allows.

The object of the invention is be first through a skin detoxifier write features of patent claim 1.

The features of the independent claim 3 defining an appropriate Applicator.

The advantages of the invention therefore result in that the skin means a detoxification first composition and a second composition. The first Composition is kept separate from the second composition. The first composition contains a first active ingredient, the chloramine T or similarly acting chloramine is. This substance is in the weakly acidic medium ent giftend with skin warfare agents, and also acts against the nerve agent VX. in the alkaline environment affects the hypochlorite formed by Chlaramin T oxi addition dativ against Sann, Cyclosarm, soman and tabun.

Furthermore chloramine T has in is application described here, a high Ent giftungspotential against other, after possible warfare agents and toxins such. B. My cotoxine. In addition, here the well-known from the literature bactericidal Action led by chloramine T. Furthermore, the first combination includes setting a second active ingredient of a salt or a dimethylglyoxime gleichwir Kende alkaline oxime salt.

This drug also acts in an alkaline medium by hydrolysis and ester divisive for sarin, cyclosarin, soman and tabun. support both drugs therefore their effect and accelerate the detoxification difficult for the accessible nerve agent VX.

The second composition also contains the active ingredient diacetyl as free Acid. This agent interacts with the alkaline component in the first composition by hydrolysis and ester hydrolysis to the detoxifying Nerve agents, thereby strengthening detoxification.

The first active ingredient and the second active ingredient of the first composition are in a suspension containing silicone-based. For the active ingredient Chloramine T be this means that it will remain stable after long storage and no chlorine is split off. Therefore, the first composition does not smell of chlorine. Because the chloramine is not decomposed, is obtained in comparison to other chloramine T PREPARATIO gen, a substantially improved storage stability.

The aforementioned suspension on the base days of Silicon further comprises the emulsifiers glyceryl and Sodium. The emulsifiers mentioned above provide a good Appli gevermögen safe and cause the emulsification of most fat-soluble C- Warfare agents and other toxic materials.

The active ingredient diacetyl the second composition is in acidic Glycerin dissolved. This gives the necessary water content, achieved a rapid pH adjustment on the skin surface and allows the solution and rapid effect of the suspended active ingredients from the first composition.

A suitable applicator for the skin detoxifying agent comprises a container for the first composition, the out with a rotatable, from the container looking orb is provided for applying. Further, the applicator comprises egg NEN lid with a sponge contained herein for receiving the second Composition, wherein in the position in which the lid on the container ar is retiert, pushes the sponge on the ball. be The advantage of this applicator is that first the second composition initially dominant on the skin is applied and then Überla of the first composition siege is. Loosen the moisture, acid and salts of the second composition and activate the chloramine-T from the first composition and thus lead proceeds to the formation of hypochlorite and to the release of chlorine, which comprises Blister agents, as well as the nerve agents and other toxic Verbin tions, broken down into non-toxic compounds.

An embodiment of the invention is described with reference to the drawings described in detail. The single FIGURE shows an applicator for Hautent giftungsmittel in perspective view.

A skin detoxifying agent for skin and nerve agents includes a first to composition and a second composition. The first composition is kept separate from the second composition. The first co composition containing a first active ingredient, the chloramine T or a similar effect the chloramine is. At the same effect chloramine may be chloramine TT act. Further, the first composition contains a second active ingredient, of a dimethylglyoxime salt or a similarly acting alkaline oxime salt. At the same effect oxime salt may be han to diacetyl-salt spindles. The second composition contains the active ingredient as diacetyl monoxime free acid. More detail on the first composition, the first Active and second active ingredient in an aqueous suspension based on silicone contain. The suspension on the basis of silicones comprising the emulsifiers ren Glycerol and sodium.

The first composition is formulated as follows:

<ul><li>- 7 percent by weight of the active ingredient chloramine T,</li><li>- 9 percent by weight of the active ingredient dimethylglyoxime disodium salt,</li><li>- 75 percent by weight of a volatile silicone oil which stabilizes the active ingredients,</li><li>- 5 weight percent of a non-volatile silicone oil, the consistency of the Suspension improves,</li><li>- 2 percent by weight of the emulsifier glycerol monostearate,</li><li>- 1.5 weight percent of the emulsifier, Natriumdodecysulfat,</li><li>- 0.25 percent by weight of the adjuvant, sodium chloride, to contact with water To activate the chloramine T,</li><li>- 0.25 weight percent of the auxiliary silica in precipitated form, to Improvement of consistency.</li></ul>

To obtain an ointment consistency of the proportion of the volatile silicone oil can ver be reduced.

Inbound to the second composition is the active ingredient diacetyl in acidic glycerol dissolved. The second composition is formulated as follows lines:

<ul><li>- 10 percent by weight of the active ingredient diacetyl monoxime,</li><li>- 60 percent by weight glycerol,</li><li>- 5 percent by weight of the acidic salt potassium bisulfate, the the chloramine T activated,</li><li>- 5 percent by weight of the emulsifier Tergitol® (mixture of nonionic Ethoxylates) enabling the solution of the active ingredients on the skin and fettlö send properties,</li><li>- 3 percent by weight of the excipient, sodium chloride, the chloramine T Akti fourth,</li><li>- 4 per cent by weight of the excipient in silica precipitated form, for Stabili tion of the suspension,</li><li>- 13 percent by weight of demineralized water as the reaction medium.</li></ul>

For detoxification of the skin area to apply the following steps: Wetting of the skin with the solution of the second composition. there is a suitable reaction medium, here water, salts, acid and a first Drug applied.

Application of the suspension of the first composition. Here, the pH is Area shifted from acidic to basic conditions, dissolved the active substances and the Poisons reacted.

A suitable applicator for the skin detoxifying agent is the only figure. The applicator <b>1</b> comprises a container <b>10</b> with the first composition. Of the Container with a rotatable ball <b>11</b> provided for applying. correspondingly the display looks the ball <b>11</b> from the vessel <b>10</b> forth. Furthermore the applicator comprises a lid <b>20</b> with a sponge contained herein <b>21</b>. which receives the second composition. If one imagines the position before, at of the lid <b>20</b> to the container <b>10</b> is locked, pressing the sponge <b>21</b> on the ball <b>11</b>, In applicator therefore lie on the application sphere<b>11</b> already sour Active and active components against which represent before the suspension of the first Composition reach the skin and prepare it for detoxification. By further unwinding of the applicator eventually outweigh the agents that in al ical medium come into effect. The plug<b>22</b> consists of resistant Silicone rubber. causes his impressions in sealed Applikatorstellung an additional dose of acidic components from the second cooperation tion.