CA2217455A1

New substituted derivatives, of biphenyl or phenylpiridine, their preparation process and the pharmaceutical compositions that contain them

Abstract

Compound of formula (I): (see fig. I) in which: R1 represents a group, substituted or unsubstituted, cycloalkyl, phenyl, naphthyl, heterocyclic, alkyl or alkenyl, A represents a bond (provided that in this case R1 is different from a C1 or C2 alkyl group); , an oxygen atom, sulfur, a group (see fig. II) a grouping (see fig. III) or a grouping (see fig. IV) (wherein Rc represents a hydrogen atom, an alkyl group or a cycloalkyl group, R2 represents a halogen atom, an alkyl group, alkenyl, alkynyl, cycloalkyl, formyl, carboxy, alkylcarbonyl, cycloalkylcarbonyl, alkoxycarbonyl, cycloalkyloxycarbonyl, optionally substituted carbamoyl, optionally substituted amino, formamido, cyano, optionally substituted amidino, optionally substituted hydroxyaminomethyl, optionally substituted amide oxime, optionally substituted hydrazono, or a group chosen from: <IMG> and <IMG> in which R21, R22, R23 are as defined in the description, R3 represents a hydrogen atom, an alkyl group, cycloalkyl or acyl, or <IMG> together form the cycle <IMG>, X represents an oxygen atom, sulfur or a group NR ", ring B represents a phenyl or pyridyl ring, Ra, Rb, identical or different, represent a hydrogen atom, halogen, an alkyl group, hydroxy, alkoxy, carboxy, polyhaloalkyl, cyano, nitro, alkoxycarbonyl, cycloalkyloxycarbonyl, amino, carbamoyl, sulfo, alkylsulfonyl e, cycloalkylsulfonyl or aminosulphonyl, their isomers as well as their addition salts with a pharmaceutically acceptable acid or base. Drugs.

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Projected expiry passed 2 October 2017, 9 years ago.

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9612111FranceA
9612111FranceA
9612111
FR19960012111

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