ATE58839T1

Compositions and method for improving wound healing

Abstract

The healing of wounds is promoted by contacting the wound surfaces with a suspension of collagen and a glycosaminoglycan that is chemotactic for fibroblasts and/or endothelial cells. Typical glycosaminoglycans that exhibit the desired chemotaxis are heparin, heparan sulfate, and alginate. Two or more glycosaminoglycans can be present in the suspensions. Collagen is present in the suspension in the order of 7-10 mg/ml; while the glycosaminoglycan is present in much lower concentrations, e.g, 250-350 µg/ml. Application of the collagen/glycosaminoglycan suspension to open wounds greatly increases the rate of healing.

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Projected expiry passed 20 February 2005, 21.6 years ago.

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58315984United States of AmericaA

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EP0154447A2European Patent Office (EPO)A2
JPS60222425AJapanA
EP0154447A3European Patent Office (EPO)A3
US4745098AUnited States of AmericaA
US4808570AUnited States of AmericaA
US4837024AUnited States of AmericaA
CA1258630ACanadaA
EP0154447B1European Patent Office (EPO)B1
AT58839TAustriaT
ATE58839T1This recordAustriaT1
DE3580769D1GermanyD1
JPH0751512B2JapanB2