ATE399151T1

2-ethyl and 2-ethylidene-19-nor-vitamin d compounds

Abstract

Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring with an ethylidene or an ethyl group. These compounds have preferential activity on mobilizing calcium from bone and either high or normal intestinal calcium transport activity which allows their in vivo administration for the treatment of metabolic bone diseases where bone loss is a major concern. These compounds are also characterized by high cell differentiation activity.

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Projected expiry passed 31 May 2021, 5.3 years ago.

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CA2410880A1CanadaA1
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AU6527201AAustraliaA
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MXPA02011820AMexicoA
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US2005043281A1United States of AmericaA1
EP1524264A2European Patent Office (EPO)A2
US2005282789A1United States of AmericaA1
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AU2001265272B2AustraliaB2
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EP1286962B1European Patent Office (EPO)B1
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EP1524264A3European Patent Office (EPO)A3