Cyclohexylphenyl vasopressin agonists
Abstract
The present invention provides compounds of the general formulas: wherein Y is NR or -(CH<SUB>2</SUB>)<SUB>n</SUB>; R is H or alkyl; "Z" represents optionally substituted phenyl or a 6-membered aromatic ring having one nitrogen atom; "W" represents a optionally substituted phenyl or 5-membered aromatic ring having one nitrogen atom; "X" represents an optionally substituted 5-membered aromatic ring having one sulfur atom; as well as methods and pharmaceutical compositions utilizing these compounds for the inducing temporary delay of urination or treatment of disorders remedied by vasopressin agonist activity, including diabetes insipidus, nocturnal enuresis, nocturia, urinary incontinence, or bleeding and coagulation disorders.
Term
Term ended
Projected expiry passed 11 April 2022, 4.5 years ago.
- Priority
- Filed
- Published
- Projected expiry
- Today
19 members in 12 offices
Priority claims1
| Document | Office | Kind | Date |
|---|---|---|---|
| 28338701 | United States of America | P |
Members19
| Document | Office | Kind | |
|---|---|---|---|
| CA2443870A1 | Canada | A1 | |
| WO02083685A1 | World Intellectual Property Organization (WIPO) | A1 | |
| US2002198191A1 | United States of America | A1 | |
| EP1381608A1 | European Patent Office (EPO) | A1 | |
| MXPA03009159A | Mexico | A | |
| BR0208824A | Brazil | A | |
| CN1514834A | China | A | |
| JP2004526771A | Japan | A | |
| US7053083B2 | United States of America | B2 | |
| US2006183734A1 | United States of America | A1 | |
| CN1294134C | China | C | |
| EP1381608B1 | European Patent Office (EPO) | B1 | |
| AT375346T | Austria | T | |
| ATE375346T1This record | Austria | T1 | |
| DE60222879D1 | Germany | D1 | |
| DK1381608T3 | Denmark | T3 | |
| US7329653B2 | United States of America | B2 | |
| ES2294130T3 | Spain | T3 | |
| DE60222879T2 | Germany | T2 |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Ceased as to paragraph 5 lit. 3 law introducing patent treatiesCeasedRER | RER |
Numbers
- Application
- 2721730
Titles2
- German
- CYCLOHEXYLPHENYL VASOPRESSIN AGONISTEN
- English
- CYCLOHEXYLPHENYL VASOPRESSIN AGONISTS
Classification
- CPC, 9
- C07D471/04
- C07D243/14
- C07D471/14
- C07D487/04
- C07D495/04
- A61P13/00
- A61P5/10
- A61P7/00
- A61P9/00
- IPC, 13
- C07D243 38
- A61K31 55
- A61K31 551
- A61K31 5513
- A61K31 5517
- A61P5 10
- A61P9 00
- A61P13 00
- C07D243 14
- C07D471 04
- C07D471 14
- C07D487 04
- C07D495 04