ATE178908T1

Lys (B28) insulins. Human insulin analogues

Abstract

Human insulin analogues having a positively charged amino acid residue, i.e. Lys or Arg, in position B28, i.e. in position 8 in the B-chain calculated from [Gly<sup>B20</sup>], and optionally being further modified in the C-terminal end of the B-chain from [Phe<sup>B24</sup>] to the C-terminal amino acid residue and optionally A21 and/or B3 being different from Asn as well as insulin preparations containing the human insulin analogues are provided.

Term

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Projected expiry passed 21 December 2009, 16.8 years ago.

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