Intranasal influenza vaccine based on virosomes

A composition comprising virosomes Influenza comprising wrapped reconstituted from influenza virus for use in inducing a systemic immune response and / or local versus the influenza antigens haemagglutinin and / or neuraminidase or derivatives thereof in a human being through a single intranasal or inhalational administration, wherein: - the viral envelopes are derived entirely from viral particles of influenza, - no lipid from an external source to the reconstituted virosomes are added, - the virosomes comprise the influenza antigens hemagglutinin and / or neuraminidase or derivatives thereof, and - an adjuvant and / or immune stimulator separately to the composition is not added.