AT537190T
High affinity antibodies to human IL-6 receptor
Abstract
The application supplying a humanized antibody or antigen-binding sheet, comprising a human IL-6 receptor (hIL-6R) union's KD is from about 500pM or less, sealed with IL-6 activity IC50 is 200pM or less. The antibody or antibody sheet and hydrophilic hIL-6R of the ratio of the detecting IL-6R there is at least twice.
Term
0.7 yearsleft in the term
Expires 1 June 2027.
- Priority
- Filed
- Granted
- Today
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91 members in 38 offices
Priority claims3
| Document | Office | Kind | Date |
|---|---|---|---|
| 81066406 | United States of America | P | |
| 84323206 | United States of America | P | |
| 2007013062 | United States of America | W |
Members91
| Document | Office | Kind | |
|---|---|---|---|
| US2007280945A1 | United States of America | A1 | |
| AU2007254831A1 | Australia | A1 | |
| CA2652976A1 | Canada | A1 | |
| WO2007143168A2 | World Intellectual Property Organization (WIPO) | A2 | |
| WO2007143168A3 | World Intellectual Property Organization (WIPO) | A3 | |
| MX2008014804A | Mexico | A | |
| ECSP088993A | Ecuador | A | |
| NO20085309L | Norway | L | |
| KR20090024690A | Republic of Korea | A | |
| CR10462A | Costa Rica | A | |
| EP2041177A2 | European Patent Office (EPO) | A2 | |
| MA30535B1 | Morocco | B1 | |
| CN101454345A | China | A | |
| GT200800272A | Guatemala | A | |
| US7582298B2 | United States of America | B2 | |
| SV2008003113A | El Salvador | A | |
| JP2009539349A | Japan | A | |
| ZA200809771B | South Africa | B | |
| TNSN08502A1 | Tunisia | A1 | |
| RU2008152443A | Russian Federation | A | |
| NZ573557A | New Zealand | A | |
| US2010316627A1 | United States of America | A1 | |
| US2010316636A1 | United States of America | A1 | |
| HN2008001792A | Honduras | A | |
| IL195393D0 | Israel | D0 | |
| ME00519B | Montenegro | B | |
| EP2374818A1 | European Patent Office (EPO) | A1 | |
| US8043617B2 | United States of America | B2 | |
| RU2433138C2 | Russian Federation | C2 | |
| EP2041177B1 | European Patent Office (EPO) | B1 | |
| AT537190TThis record | Austria | T | |
| US8080248B2 | United States of America | B2 | |
| US2012003697A1 | United States of America | A1 | |
| BRPI0712224A2 | Brazil | A2 | |
| US2012045440A1 | United States of America | A1 | |
| DK2041177T3 | Denmark | T3 | |
| PT2041177E | Portugal | E | |
| UA97645C2 | Ukraine | C2 | |
| AU2007254831B2 | Australia | B2 | |
| ES2377579T3 | Spain | T3 | |
| SI2041177T1 | Slovenia | T1 | |
| HRP20120175T1 | Croatia | T1 | |
| US8183014B2 | United States of America | B2 | |
| NZ587107A | New Zealand | A | |
| US8192741B2 | United States of America | B2 | |
| CN102585002A | China | A | |
| CN101454345B | China | B | |
| RS52176B | Serbia | B | |
| PL2041177T3 | Poland | T3 | |
| US2012258098A1 | United States of America | A1 | |
| MY147468A | Malaysia | A | |
| EP2374818B1 | European Patent Office (EPO) | B1 | |
| DK2374818T3 | Denmark | T3 | |
| PT2374818E | Portugal | E | |
| ES2398076T3 | Spain | T3 | |
| SI2374818T1 | Slovenia | T1 | |
| HRP20130228T1 | Croatia | T1 | |
| PL2374818T3 | Poland | T3 | |
| US2013157313A1 | United States of America | A1 | |
| RS52643B | Serbia | B | |
| IL195393A | Israel | A | |
| JP5307708B2 | Japan | B2 | |
| US8568721B2 | United States of America | B2 | |
| JP2013226143A | Japan | A | |
| US2014255390A1 | United States of America | A1 | |
| US2014255995A1 | United States of America | A1 | |
| KR101464502B1 | Republic of Korea | B1 | |
| CA2652976C | Canada | C | |
| JP5805703B2 | Japan | B2 | |
| CY1112456T1 | Cyprus | T1 | |
| JP2016026171A | Japan | A | |
| US9308256B2 | United States of America | B2 | |
| CY1113708T1 | Cyprus | T1 | |
| US2016229916A1 | United States of America | A1 | |
| MY159787A | Malaysia | A | |
| JP6140777B2 | Japan | B2 | |
| NO340778B1 | Norway | B1 | |
| NO2017060I1 | Norway | I1 | |
| LUC00050I1 | Luxembourg | I1 | |
| LTPA2017038I1 | Lithuania | I1 | |
| HUS1700050I1 | Hungary | I1 | |
| LUC00050I2 | Luxembourg | I2 | |
| NL300911I2 | Netherlands (Kingdom of the) | I2 | |
| US9884916B2 | United States of America | B2 | |
| LTC2041177I2 | Lithuania | I2 | |
| US2019256606A1 | United States of America | A1 | |
| US10584173B2 | United States of America | B2 | |
| BRPI0712224B1 | Brazil | B1 | |
| US2021009698A1 | United States of America | A1 | |
| BRPI0712224B8 | Brazil | B8 | |
| US11370843B2 | United States of America | B2 |
Numbers
- Application
- 7777380
Titles2
- German
- HOCHAFFINE ANTIKÖRPER GEGEN DEN HUMANEN IL-6- REZEPTOR
- English
- HIGH ANTIBODY TO THE HUMAN IL-6 RECEPTOR
Classification
- CPC, 18
- C07K16/2866
- C07K16/28
- A61K2039/505
- A61P1/00
- A61P1/04
- A61P19/02
- A61P29/00
- A61P37/00
- A61P37/02
- C07K2317/21
- C07K2317/76
- C07K2317/92
- C07K16/26
- C07K2317/14
- C12N15/11
- A61K39/00
- C07K2317/56
- C07K2317/565
- IPC, 3
- C07K16 28
- A61K39 00
- C12N15 13