Loadable polyphosphazene-comprising particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
Abstract
The present invention relates to particles for use in the treatment and / or diagnosis process. And the particles comprises a polyester which may be present in the outer coating of the particles throughout the particle or [bis (trifluoroethoxy) phosphazene] and / or derivatives thereof. And the particles also include a core having a hydrogel formed from an acrylic polymer. Barium sulfate is provided as a coating on the core of the particles, or may be absorbed in the particle core. It can be used to block the particles to at least a portion of a mammalian blood vessel to minimize the flow of the mammalian tissue or deliver an active agent to the local areas of the mammalian body by at least one particle in contact with the local area Sikkim. In addition, the particles of the blood stream by injection or mammalian enhanced ultrasound imaging to track the use of the particles as the active agent for oral administration comprising a sustained-release preparation is useful. The particles may contain an agent to increase the density to achieve buoyancy in the suspension to a.Microparticles, poly [bis (trifluoro-ethoxy a) phosphazene], a contrast agent, the acrylic polymer, barium sulfate
Term
Term ended
Expired 24 October 2025, 0.9 years ago.
- Priority
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73 members in 16 offices
Priority claims3
| Document | Office | Kind | Date |
|---|---|---|---|
| 62172904 | United States of America | P | |
| 68430705 | United States of America | P | |
| 2005004007 | International Bureau of the World Intellectual Property Organization (WIPO) | W |
Members73
| Document | Office | Kind | |
|---|---|---|---|
| US2006088476A1 | United States of America | A1 | |
| AU2005298344A1 | Australia | A1 | |
| CA2584122A1 | Canada | A1 | |
| WO2006046155A2 | World Intellectual Property Organization (WIPO) | A2 | |
| TW200626178A | Taiwan Province of China | A | |
| WO2006046155A3 | World Intellectual Property Organization (WIPO) | A3 | |
| US2006267999A1 | United States of America | A1 | |
| WO2006127266A2 | World Intellectual Property Organization (WIPO) | A2 | |
| US2006293932A1 | United States of America | A1 | |
| US2006293979A1 | United States of America | A1 | |
| US2007030282A1 | United States of America | A1 | |
| WO2006127266A3 | World Intellectual Property Organization (WIPO) | A3 | |
| EP1804773A2 | European Patent Office (EPO) | A2 | |
| IL182650D0 | Israel | D0 | |
| KR20070084341A | Republic of Korea | A | |
| CN101090710A | China | A | |
| US2008102029A1 | United States of America | A1 | |
| US2008113029A1 | United States of America | A1 | |
| JP2008517899A | Japan | A | |
| BRPI0518383A2 | Brazil | A2 | |
| HK1116058A1 | Hong Kong, China | A1 | |
| AU2007356895A1 | Australia | A1 | |
| CA2694408A1 | Canada | A1 | |
| WO2009014549A1 | World Intellectual Property Organization (WIPO) | A1 | |
| US2010028260A1 | United States of America | A1 | |
| EP2185132A1 | European Patent Office (EPO) | A1 | |
| KR20100074109A | Republic of Korea | A | |
| CN101820861A | China | A | |
| JP2010534266A | Japan | A | |
| US7860782B2 | United States of America | B2 | |
| AU2005298344B2 | Australia | B2 | |
| EP1804773B1 | European Patent Office (EPO) | B1 | |
| AT503465TThis record | Austria | T | |
| ATE503465T1 | Austria | T1 | |
| DE602005027229D1 | Germany | D1 | |
| ES2360542T3 | Spain | T3 | |
| US8019828B2 | United States of America | B2 | |
| US8019843B2 | United States of America | B2 | |
| US8024778B2 | United States of America | B2 | |
| JP4885866B2 | Japan | B2 | |
| CN101090710B | China | B | |
| KR101153785B1 | Republic of Korea | B1 | |
| AU2007356895B2 | Australia | B2 | |
| US8318209B2 | United States of America | B2 | |
| EP2545906A1 | European Patent Office (EPO) | A1 | |
| IL182650A | Israel | A | |
| MY147841A | Malaysia | A | |
| US2013052142A1 | United States of America | A1 | |
| CA2584122C | Canada | C | |
| CA2694408C | Canada | C | |
| JP2014039836A | Japan | A | |
| KR101506557B1 | Republic of Korea | B1 | |
| BRPI0721916A2 | Brazil | A2 | |
| US9107850B2 | United States of America | B2 | |
| US9114162B2 | United States of America | B2 | |
| JP5775912B2 | Japan | B2 | |
| US2015250736A1 | United States of America | A1 | |
| US2015258224A1 | United States of America | A1 | |
| EP2185132B1 | European Patent Office (EPO) | B1 | |
| ES2564151T3 | Spain | T3 | |
| US9511153B2 | United States of America | B2 | |
| US9597419B2 | United States of America | B2 | |
| EP2545906B1 | European Patent Office (EPO) | B1 | |
| US2017172933A1 | United States of America | A1 | |
| IL203491A | Israel | A | |
| IL203491B | Israel | B | |
| US2021023015A1 | United States of America | A1 | |
| US10973770B2 | United States of America | B2 | |
| US11052050B2 | United States of America | B2 | |
| US2021290555A1 | United States of America | A1 | |
| US2021299056A9 | United States of America | A9 | |
| US11426355B2 | United States of America | B2 | |
| US2022362161A1 | United States of America | A1 |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Ceased as to paragraph 5 lit. 3 law introducing patent treatiesCeasedRER | RER |
Numbers
- Application
- 5825096
Titles2
- German
- BELADBARE POLYPHOSPHAZENHALTIGE TEILCHEN FÜR THERAPEUTISCHE UND/ODER DIAGNOSTISCHE ANWENDUNGEN SOWIE HERSTELLUNGS- UND VERWENDUNGSVERFAHREN DAFÜR
- English
- LOADABLE POLYPHOSPHAZINE-HOLDING PARTICLES FOR THERAPEUTIC AND / OR DIAGNOSTIC APPLICATIONS AND MANUFACTURING AND USE METHOD THEREFOR
Classification
- CPC, 16
- A61K9/5031
- A61K9/16
- A61K9/1641
- A61K9/5073
- A61K49/0419
- A61P1/00
- A61P7/00
- A61P15/00
- A61P35/00
- A61K9/1694
- A61K9/50
- A61K49/04
- A61K49/22
- A61K9/5078
- A61K9/5089
- A61K49/0404
- IPC, 3
- A61K9 16
- A61K9 50
- A61K9 51