Compositions and methods for increasing bone mineralisation

[Subject] a bone -- mineralization -- offer of a constituent and a method which may be used in order to deal with extensive various states with desirable being used in order to increase an operation, therefore increasing the amount of bony tissues. [Means for Solution] a new class or a family of TGF*beta binding protein -- anda bone -- mineralization -- a method for using assay for choosing a molecule for increasing an operation, and such a molecule, An antibody specifically combined with these TGF*beta binding protein, nucleic acid molecules which code these TGF*beta binding protein and these nucleic acid molecules, and an oligonucleotide hybridized specifically. [Chosen drawing] Nothing