Antibodies against fibroblast growth factor 23

A objective of the present invention provides anti-fibroblast Growth factor-23 antibody. Namely, wherein the control phosphate or metabolism the group comprising metabolism an antibody, and (a), (b), (c) antibody, wherein the antibody comprising the polypeptide of amino acid sequence by use of one of shown in SEQ ID NO: 1 or comprising one or more from the amino acid sequence of SEQ ID NO: 1 as a deletion, wherein the or incremental an amino acid sequence of amino acid and at most obtained, and a fibre growth factor 23 active polypeptide immune animals to obtain. the (a) a recognition to SEQ ID NO: 1 in the amino acid sequence in a 180th to 194th or 237th amino acid sequence of said 251st. the (b) a collection number of FERM BP-7838 FERM, BP-7839, FERM, BP-7840 antibody or BP-8268 FERM hybridoma producing. the (c) one of the collection number of FERM BP-7838 FERM, BP-7839, FERM, BP-7840 one of competition antibody or BP-8268 FERM hybridoma producing.