AT407934T

Fused ring azadecalin glucocorticoid receptor modulators

Abstract

A compound having the formula: R 1. (Omitted) wherein L 1 and L 2 are independently selected from a bond, O, S, S (O), S (O2), C (O), C (O) O, C (O) NH members , substituted or unsubstituted alkylene and substituted or unsubstituted heteroalkylene; the dashed line b is optionally a bond; ring A is a member selected from heterocycloalkyl substituted 5 to 6 members or unsubstituted heteroaryl and substituted or unsubstituted; R 1 is a member selected from hydrogen, substituted or unsubstituted, substituted or unsubstituted heteroalkyl, substituted cycloalkyl or unsubstituted or substituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, OR 1A, NR 1C R 1D, -C (O) NR 1C R 1D, -C (O) oR 1A, wherein R 1A is a member selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, heterocycloalkyl substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl and substituted or unsubstituted; R 1C and R 1D are independently selected from substituted or or or or unsubstituted alkyl, substituted heteroalkyl, unsubstituted substituted unsubstituted cycloalkyl, substituted heterocycloalkyl unsubstituted aryl, substituted or unsubstituted members and substituted or unsubstituted heteroaryl, wherein R 1C and R 1D are optionally joined to form a substituted or unsubstituted with the nitrogen to which they are attached, wherein said ring optionally comprises an additional ring nitrogen ring, and R 2 is a member selected from substituted or unsubstituted alkyl, substituted heteroalkyl or unsubstituted cycloalkyl, substituted or unsubstituted, substituted heterocycloalkyl or unsubstituted aryl substituted or unsubstituted, substituted or unsubstituted heteroaryl, S (O2) R 2A, S (O2) NR 2B R 2C and = NOR 2D, wherein R 2A , R 2B, R 2C, and 2D R are independently selected from substituted or or or or unsubstituted alkyl, substituted heteroalkyl, unsubstituted substituted unsubstituted cycloalkyl, substituted heterocycloalkyl unsubstituted aryl, substituted or unsubstituted members and substituted or unsubstituted heteroaryl .

Term

No projected expiry on record.

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30 members in 17 offices

This recordMember, by publication datePriority claim7 more offices are in the list below

Priority claims1

Priority claims
DocumentOfficeKindDate
55183604United States of AmericaP

Members30

Family members, oldest first
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AU2005222421A1AustraliaA1
CA2558899A1CanadaA1
WO2005087769A1World Intellectual Property Organization (WIPO)A1
EP1735308A1European Patent Office (EPO)A1
IL177982A0IsraelA0
KR20070029684ARepublic of KoreaA
CN101027301AChinaA
JP2007528417AJapanA
US2007281928A1United States of AmericaA1
HK1104813A1Hong Kong, ChinaA1
EP1735308B1European Patent Office (EPO)B1
AT407934TThis recordAustriaT
ATE407934T1AustriaT1
DE602005009687D1GermanyD1
PT1735308EPortugalE
DK1735308T3DenmarkT3
ZA200608306BSouth AfricaB
ES2313317T3SpainT3
NZ550362ANew ZealandA
AU2005222421B2AustraliaB2
US7928237B2United States of AmericaB2
CN101027301BChinaB
US2011166110A1United States of AmericaA1
JP4931794B2JapanB2
US2012225856A1United States of AmericaA1
KR101185281B1Republic of KoreaB1
IL177982AIsraelA
CA2558899CCanadaC
US8557839B2United States of AmericaB2
US2014179671A1United States of AmericaA1