Novel thiourea derivatives and the pharmaceutical compositions containing the same

The invention relates to the comprising the derivative pharmaceutical composition as vanilloid receptor (VR) conditioner's novel thiourea derivative. To asthma and chronic obstructive pulmonary disease, skin, eye or mucosal membrane is constituent vanilloid receptor activity related disease such as a, pain, depression, and mental disease and process for use, migraine, arthralgia, and mental, the dementia, diabetes and mental, wherein the neurodegenerative, the nervousness skin disease, and stroke urethra urinary bladder allergy, the irritant from syndrome and respiratory diseases and for heat treating, duodenal ulcer, the intestinal inflammatory disease and inflammatory disease. The invention also provides for preventing or treating the diseases' pharmaceutical composition.