Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group

The invention is target to provide the CRF receptor antagonist, for use as involving CRF the treatment or prevention of a disease effectively, desipramine has such as depression, anxiety disorder, Alzheimer's, huntington's disease and Hanging dibenzothiazepine Tingdu, the diet disorder, hypertension, gastric disease, drug dependency, epilepsy, cerebral antigen and ischemia brain, hydro-cephalus, a wound flesh, inflammation and immune related disease, for grains of a, irritable bowel syndrome, the sleep disorder, epilepsy, dermatitis, wherein the ABR+OBR process in. The solution of the pyrrole and or from pyridine derivatives of an amino of the formula I] represents a high affinity to the CRF coupling agent, and effective treatment involving of CRF.