Nova Patents
AT380189T

2-amino-5-benzoylthiazole npy antagonists

Abstract

1. Compounds of formula IgdeRoznachaet amino, aryl or heteroaryl, is hydrogen or alkyl, is hydrogen, alkyl or halogen; R-alkyl or halogen, is hydrogen, alkyl or halogen, a is 0 or 1, ab is 0, 1 or 2 and their pharmaceutically acceptable salts and esters efiry.2. Compounds according to claim 1, wherein R vodorod.3. Compounds according to claim 1, wherein R vodorod.4. Compounds according to claim 1, wherein R alkil.5. Compounds according to claim 4, wherein R metil.6. Compounds according to claim 1, wherein R vodorod.7. Compounds according to claim 1, wherein b is equal to 0.8. Compounds according to claim 1, wherein a is 0.9. Compounds according to claim 1, wherein a is 1.10. Compounds according to claim 1, wherein R monoalkylamino, dialkylamino, phenyl, thiophenyl or pyrrolidinyl, wherein phenyl, thiophenyl and pyrrolidinyl are optionally substituted with one to three substituents independently selected from the group consisting of alkyl, halogen, alkoxy, trifluoromethoxy, nitro and triftormetil.11. Compounds according to claim 10, wherein R thiophen-3-yl, 3-fluorophenyl, 4-fluorophenyl, 2-methylphenyl, 2-methoxy-5-methylphenyl, dimethylamino, thiophene-2-yl, 5-fluoro-2-methylphenyl, 2,4-difluorophenyl, 5-chloro-2-methoxyphenyl, 2-fluorophenyl, 3-fluorophenyl, 2-chloro-5-trifluoromethylphenyl, 3-nitrophenyl, 4-nitrophenyl or 4-metoksifenil.12. Compounds according to claim 1, selected from the group consisting of {4- [5- (2-methylbenzoyl) thiazol-2-ylamino] -phenyl} -amide thiophene-2-sulfonic acid {4- [5- (2-methylbenzoyl) -thiazol -2-ylamino] -phenyl} -amide thiophene-3-sulfonic acid, 5- {4- [5- (2-methylbenzoyl) thiazol-2-ylamino] -phenyl} -amide chlorothiophene-2-sulfonic acid, 2-fluoro-N- {4- [5- (2-methylbenzoyl) thiazol-2-ylamino] -phenyl} -benzenesulfonamide, 3-fluoro-N- {4- [5- (2-methylbenzoyl) thiazol-2-ylamino] -phenyl} -benzenesulfonamide,

Term

No projected expiry on record.

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18 members in 14 offices

This recordMember, by publication datePriority claim4 more offices are in the list below

Priority claims1

Priority claims
DocumentOfficeKindDate
03017634European Patent Office (EPO)A

Members18

Family members, oldest first
DocumentOfficeKind
AU2004263311A1AustraliaA1
CA2533463A1CanadaA1
US2005038089A1United States of AmericaA1
WO2005014592A1World Intellectual Property Organization (WIPO)A1
KR20060037435ARepublic of KoreaA
MXPA06001570AMexicoA
EP1658288A1European Patent Office (EPO)A1
BRPI0413500ABrazilA
CN1852907AChinaA
JP2007501823AJapanA
US7250431B2United States of AmericaB2
RU2006107444ARussian FederationA
EP1658288B1European Patent Office (EPO)B1
AT380189TThis recordAustriaT
DE602004010529D1GermanyD1
ES2297437T3SpainT3
CN100422179CChinaC
DE602004010529T2GermanyT2