In-vitro method for the production of a homologous stented tissue-engineered heart valve

An in vitro method for producing a heart valve homologous, comprising the following steps: - providing a biologically degradable carrier (scaffold) - colonization of the carrier with fibroblasts and / or myofibroblasts counterparts for forming a matrix connective tissue, - in a given case, colonization of the connective tissue matrix with endothelial cells - fixing the matrix on a non-degradable or poorly degradable frame construction (stent), wherein the connective tissue matrix settled in a given case with cells endothelial is introduced, before and / or after fixing to the structural construction, in a pulsatile flow chamber in which can be subjected to increasing flow rates, and the flow rate increases continuously or discontinuously.