N-biphenylcarbonyl- and n-phenylpyridylcarbonyl substituted bi- and tricyclic azepines and diazepines as vasopressing agonists

Type (I) or (II) compounds or its can medicinal salt or Qian drug forms: which y is selected since NR or-(CH2) n of part; which r is hydrogen or (C1-C6) low-level alkyl, and n is 1; (Z) representative (1) benzene ring, by in benzene ring can any selected is a or two a independent to selected since following of replaced base replaced: hydrogen, and (C1-C6) low-level alkyl, and halogen, and cyanide base, and CF3, and hydroxy, and (C1-C6) low-level n-oxygen base, and (C1-C6) low-level n-oxygen base Carbonyl, and carboxy, and -CONH2, and-CONH[(C1-C6) low-level alkyl], and-CON[(C1-C6) low-level alkyl]2; or (2) has a nitrogen Atomic of 6-Yuan Fang family (not saturated) hybrid ring, by in hybrid ring can any selected is (C1-C6) low-level alkyl, and halogen or (C1-C6) low-level n-oxygen base replaced; (w) representative (1) benzene ring, by in benzene ring can any selected is a or two a independent to selected since following of replaced base replaced: hydrogen, and (C1-C6) low-level alkyl, and halogen, and cyanide base, and CF3, and hydroxy, and (C1-C6) low-level n-oxygen base, and or (C1-C6) low-level n-oxygen base Carbonyl, and carboxy, and-CONH2, and-CONH[(C1-C6) low-level alkyl], and-CON[(C1-C6) low-level alkyl]2; or (2) has a nitrogen Atomic of 5-Yuan Fang family (not saturated) hybrid ring, by in hybrid ring can any selected is (C1-C6) low-level alkyl, and (C1-C6) low-level n-oxygen base or halogen replaced; or (3) has a nitrogen Atomic of 6-Yuan Fang family ( Not saturated) hybrid ring, by in hybrid ring can any selected is (C1-C6) low-level alkyl, and halogen or (C1-C6) low-level n-oxygen base replaced; (x) representative has a sulfur Atomic of 5-Yuan Fang family (not saturated) hybrid ring, by in hybrid ring can any selected is (C1-C6) low-level alkyl, and halogen or (C1-C6) low-level n-oxygen base replaced; R1 is type (o or n) by shows part, and R2, and R3, and R7, and R8 and R9 independent to selected since hydrogen, and (C1-C3) low-level alkyl, and OCH3, and halogen, and CF3,-SCH3, OCF3, SCF3, or CN.