Novel b7-4 molecules and uses therefor

The invention also relates to isolated nucleic acid molecules B7-4 which encode new B7-4 polypeptides. The invention also relates to antisense nucleic acid molecules, recombinant expression vectors containing B7-4 nucleic acid molecules, host cells to which expression vectors have been introduced, human transgenic animals into which a B7-4 gene was introduced or in which a B7-4 gene was destroyed. The invention also relates to isolated B7-4 proteins, fusion proteins, antigenic peptides and anti-B7-4 antibodies. The present invention also provides diagnostic, screening and therapeutic methods using compositions according to the invention. HE