Pyrrolo[2,3-d]pyrimidine derivatives which are antagonists of adenosine A1, A2A, and A3

A compound having the structure wherein R1 is and R2 is a hydrogen atom; or NR1R2 together are wherein R3 is a substituted or unsubstituted phenyl group, a pyrrole group, a group tiofe- not, a furan group, a thiazole group, an imidazole group, a triazole group, a pyrazole group, one pyridine group, a group -pyridone 2 (1H), an -pyridone group 4 (1H), an pyrazine group, a pyrimidine group, a pyridazine group, isothiazole group, a zol isoxa- group, an oxazole group, tetrazole, a naphthyl group, a tetraline group, a benzofuran group, a benzothiophene group, a 2, 3-dihydro a 1H-indole group, an indolyl group, a benzpyrazole group, a 1, 3-benzodioxole, a group benzoxazol a purine group, a coumarin group, a chromone group, a quinolyl group, a tetrahydroquinoline group, an isoquinoline group, a benzimidazole group, a quinazoli- na group, a pteridine group, a group -quinolona 2 (1H), an group 1 (2H) -isoquinolone, a 1, 4-benzisoxazina a benzothiazole group, a quinoxaline group, a quinoline-N-oxide group, an isoquinoline-N-oxide group, a quinoxaline-N-oxide, an oxide quinazoline-N-group, a benzoxazine group, a phthalazine group or a cinnoline group; wherein R5 is a hydrogen atom, a CH3 group, an alkyl group substituted or unsubstituted aryl group or a phenyl group.