AT329579T

Inhibitors of crystallization in a solid dispersion

Abstract

Problem to be solved.To provide novel solid dispersion pharmaceutical formulations which demonstrate an inhibition of crystallization.

Solution.A solid pharmaceutical composition contains: a moleculardispersion of ritonavir (ABT-538) ;a hydrophilic, amorphous polymer selected from the group consisting of polyvinylpyrrolidone (PVP) and hydroxypropylmethylcellulose (HPMC;and matrix comprising a water soluble carrier which is selected from the group consisting of polyethylene glycol (PEG), pentaerythritol, pentaerythritol tetraacetate, polyoxyethylene stearate, and poly-epsilon-caprolacton. Thematrix includes an amorphous region where the ritonavir resides.

Copyright (C) 2014, JPO&INPIT

Term

No projected expiry on record.

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WO0134119A2World Intellectual Property Organization (WIPO)A2
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EP1175205A2European Patent Office (EPO)A2
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JP2003513904AJapanA
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ATE329579T1AustriaT1
DE60028754D1GermanyD1
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