Functional genomics using zinc finger proteins

(57) Summary book invention offers the method of identifying the biological functions of a candidate gene, and this method, (i) process; (ii) which chooses the 1st candidate gene -- the 1st zinc finger protein combined with the 1st target region of this 1st candidate gene --and process; (iii) which offers the 2nd zinc finger protein combined with the target region of the 2nd gene -- this 1st zinc finger protein the 1st cell under the conditions in contact with the 1st candidate gene, culture and And this 2nd zinc finger protein is the process of culturing the 2nd cell under the conditions in contact with the 2nd candidate gene, Here these 1st and 2nd zinc finger protein, It is the process of adjusting revelation of the 1st and 2nd candidate genes, and a process assayed about the (iv) -chosen phenotype, and the process of identifying whether this 1st candidate gene being connected with this selected phenotype by this is included.