AT304522T

Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoidane derivatives

Abstract

A compound of Formula I wherein: R1 and R2 are independently hydrogen, C1-C8alkyl, C2-C8, C2-C8, phenyl (CH2) not substituted phenyl (CH2) n, where one of R1 and R2 is different from hydrogen; R4 and R5 are independently hydrogen, halo, C-C8 alkyl, C2-C8, C2-C8, phenyl (CH2) not substituted phenyl (CH2) n, NO2, CN, CF3, C1-C8, CO2R6, tetrazolyl , NH (C1-C8), N (alkyl C-C8) 2 or SO2R6, R3 is hydrogen or C1-C8 alkyl; R6 is hydrogen, C1-C8 alkyl, phenyl (CH2) not substituted phenyl (CH2) n; n is an integer from 0 to 4 inclusive; or a salt, pharmaceutically acceptable ester or amide thereof.

Term

No projected expiry on record.

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15 members in 11 offices

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Priority claims
DocumentOfficeKindDate
20199600United States of AmericaP
0113254United States of AmericaW

Members15

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CA2405611A1CanadaA1
WO0183425A1World Intellectual Property Organization (WIPO)A1
AU5564601AAustraliaA
MXPA02009948AMexicoA
EP1284958A1European Patent Office (EPO)A1
BR0110519ABrazilA
JP2003531883AJapanA
US2003220382A1United States of AmericaA1
EP1284958B1European Patent Office (EPO)B1
AT304522TThis recordAustriaT
ATE304522T1AustriaT1
US6949575B2United States of AmericaB2
DE60113407D1GermanyD1
ES2248315T3SpainT3
DE60113407T2GermanyT2