Methods and compositions for treating pain of the mucous membrane

In one aspect, the invention provides compositions and methods that provide long-lasting local anesthesia and effective pain relief. The compositions of the invention can be applied topically on the affected area, for example, via a dosing applicator adapted for spraying or adapted for use with a cannula area. When applied topically, the compositions of the invention provide a powerful local anesthetic effect, despite the low anesthetic concentration. Therefore, the compositions of the invention provide significant pain relief with low systemic absorption and, therefore low systemic toxicity. The compositions of the invention in addition to the ability to remain on the affected area for extended periods, hydrate and soothe. In one embodiment, the compositions of the invention may be applied topically directly to the affected to relieve pain in a subject on any area of ​​the body of unsujeto area. In another embodiment, the compositions of the invention are useful for topical application to a mucous membrane of a subject, to induce a local anesthetic effect of long duration, thereby alleviating the pain from mucositis, such as mucosal inflammation, abrasions, ulcerations, and lesions, without systemic absorption signifier. In another embodiment, the compositions of the invention are useful for topical application to the site of dental surgery, such as root canal surgery or tooth extraction, to induce a local anesthetic effect of long duration, thus relieving the surgical pain, without significant systemic absorption.