3-spiro-indolin-2-one derivatives as vasopressin and/or oxytocin receptor ligands
Abstract
Under the present invention involves a dihydro-indol-ketone derivatives: where: w represents a-CH2-or-SO2-groups; Cy with their carbon to form the key link of non-aromatic saturated or unsaturated hydrocarbon rings in the C3-C12, the Central Visual case may be heavy or be of one or more (C1-C7) alkyl substituted, described substituent can be replaced one or more times on the same carbon atoms or alkyl substituted by C3-C6 Spiro; T representatives (C1-C4) Sub-alkyl, alkylidene group depends on the specific situation (C3-C6) Asia naphthenic discontinuous, alkylidene group depending on the specific circumstances of the case are described (C1-C3) alkyl replaced one or more times on the same carbon atoms; or t representatives directly connected to key; Z representative of particular amino; R1, R2, and R3 and R4, or such as hydrogen or halogens, alkyl substituents. The invention available compounds against leaf after vasopressin and/or drug oxytocin receptor affinity.
Term
No projected expiry on record.
- Priority
- Filed
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- Today
55 members in 34 offices
Priority claims8
| Document | Office | Kind | Date |
|---|---|---|---|
| 9512533 | France | A | |
| 9512533 | France | A | |
| 9601666 | France | W | |
| 9601666 | France | W | |
| 9512533 | – | – | – |
| 9601666 | – | – | – |
| FR19950012533 | – | – | – |
| WO1996FR01666 | – | – | – |
Members55
| Document | Office | Kind | |
|---|---|---|---|
| FR2740136A1 | France | A1 | |
| CA2235686A1 | Canada | A1 | |
| WO9715556A1 | World Intellectual Property Organization (WIPO) | A1 | |
| AU7308096A | Australia | A | |
| ZA968945B | South Africa | B | |
| FR2740136B1 | France | B1 | |
| IS4714A | Iceland | A | |
| NO981817D0 | Norway | D0 | |
| NO981817L | Norway | L | |
| CZ126798A3 | Czechia | A3 | |
| TR199800719T2 | Türkiye | T2 | |
| SK49098A3 | Slovakia | A3 | |
| PL326555A1 | Poland | A1 | |
| MX9803269A | Mexico | A | |
| EP0873309A1 | European Patent Office (EPO) | A1 | |
| AR004225A1 | Argentina | A1 | |
| EE9800151A | Estonia | A | |
| CN1202886A | China | A | |
| BR9611198A | Brazil | A | |
| HU9900331A2 | Hungary | A2 | |
| HUP9900331A2 | Hungary | A2 | |
| KR19990067056A | Republic of Korea | A | |
| JPH11509232A | Japan | A | |
| HK1016596A1 | Hong Kong, China | A1 | |
| HU9900331A3 | Hungary | A3 | |
| HUP9900331A3 | Hungary | A3 | |
| US5994350A | United States of America | A | |
| NZ320352A | New Zealand | A | |
| AU715841B2 | Australia | B2 | |
| US6046341A | United States of America | A | |
| IN185328B | India | B | |
| RU2167864C2 | Russian Federation | C2 | |
| KR100298925B1 | Republic of Korea | B1 | |
| NO310974B1 | Norway | B1 | |
| JP2001302631A | Japan | A | |
| TW474917B | Taiwan Province of China | B | |
| JP3274471B2 | Japan | B2 | |
| IL124002A | Israel | A | |
| EP0873309B1 | European Patent Office (EPO) | B1 | |
| AT229940TThis record | Austria | T | |
| ATE229940T1 | Austria | T1 | |
| DE69625517D1 | Germany | D1 | |
| DK0873309T3 | Denmark | T3 | |
| CN1106384C | China | C | |
| SI0873309T1 | Slovenia | T1 | |
| DE69625517T2 | Germany | T2 | |
| UA59345C2 | Ukraine | C2 | |
| ES2191769T3 | Spain | T3 | |
| MY115864A | Malaysia | A | |
| PL187093B1 | Poland | B1 | |
| IS1949B | Iceland | B | |
| EE04433B1 | Estonia | B1 | |
| SK284546B6 | Slovakia | B6 | |
| CZ295585B6 | Czechia | B6 | |
| CA2235686C | Canada | C |
1 legal event, as the office reported them to INPADOC
Events
| Event | Code | |
|---|---|---|
| Publication of translation of european patent specificationUEP | UEP |
Numbers
- Publication, DOCDB
- 229940
- Publication, EPODOC
- AT229940T
- Application
- 96934967
- Application, DOCDB
- 96934967
- Application, EPODOC
- AT19960934967T
Titles2
- German
- 3-SPIRO-INDOLIN-2-ONDERIVATE ALS LIGANDEN DER VASOPRESSIN UND/ODER DER OCYTOCIN REZEPTOREN
- English
- 3-SPIRO-INDOLIN-2-ONDERIVATES AS LIGANDS OF VASOPRESSIN AND / OR OCYTOCIN RECEPTORS
Classification
- CPC, 31
- C07D401/12
- A61P1/00
- C07D209/96
- A61P1/04
- C07D403/12
- A61P1/16
- A61P3/00
- A61P3/10
- A61P5/00
- A61P5/10
- A61P11/00
- A61P7/04
- A61P13/12
- A61P7/10
- A61P15/00
- A61P9/00
- A61P25/00
- A61P9/04
- A61P25/06
- A61P9/10
- A61P25/18
- A61P9/12
- A61P25/22
- A61P25/28
- A61P25/30
- A61P25/34
- A61P27/02
- A61P27/06
- A61P27/12
- A61P35/00
- A61P43/00
- IPC, 42
- C07D209 54
- A61K31 40
- A61K31 403
- A61K31 404
- A61K31 4427
- A61K31 445
- A61K31 454
- A61K31 496
- A61K31 535
- A61K31 5377
- A61K31 541
- A61K45 00
- A61P1 00
- A61P1 04
- A61P1 16
- A61P3 10
- A61P5 00
- A61P7 04
- A61P7 10
- A61P9 00
- A61P9 04
- A61P9 10
- A61P9 12
- A61P11 00
- A61P13 12
- A61P15 00
- A61P25 00
- A61P25 06
- A61P25 18
- A61P25 22
- A61P25 28
- A61P25 30
- A61P25 34
- A61P27 02
- A61P27 06
- A61P27 12
- A61P35 00
- A61P43 00
- C07D209 96
- C07D401 12
- C07D403 12
- C07D413 12