Powder composition of hydroxypropyl betacyclodextrin and process for preparing the same

The invention relates to a process for the preparation and preparation of powdery hydroxypropyl-β-cyclodextrin. The powdered hydroxypropyl-β-cyclodextrin composition of the present invention contains less than 25 wt.% Of 100 μm of particulate matter and a dissolution time of 20 wt.% Dry solids in the aqueous medium at 21 ° C shorter than 5 min. Powdered hydroxypropyl-β-cyclodextrin compositions are prepared by a process according to the invention by preparing a solution of at least 30 wt% of the hydroxypropyl β-cyclodextrin of dry matter, - spraying this solution in fine droplets with a stirring hydroxypropyl- β-cyclodextrin particles whose temperature is maintained between 40 ° C and 110 ° C, so that the mass of the powder never drops to less than half the weight of the solution per hour, - dry the powder and the coarse solution; and - a portion of the formulation after drying is, as appropriate, returned to the process to form a novel hydroxypropyl -? - cyclodextrin powder. The compositions of the invention can be used in the pharmaceutical industry, the cosmetics industry and the production of agrochemicals in particular. The advantage of the compositions of the invention is that they dissolve very quickly in water, readily flowable and extruded. ŕ The compositions of the invention can be used in the pharmaceutical industry, the cosmetics industry and the production of agrochemicals in particular. The advantage of the compositions of the invention is that they dissolve very quickly in water, readily flowable and extruded. ŕ The compositions of the invention can be used in the pharmaceutical industry, the cosmetics industry and the production of agrochemicals in particular. The advantage of the compositions of the invention is that they dissolve very quickly in water, readily flowable and extruded. ŕ